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Table 2 Logistic regression analysis for factors associated with prolonged duration of viral clearance among all patients (n = 706)

From: Factors associated with prolonged duration of viral clearance in non-severe SARS-CoV-2 patients in Osaka, Japan

 

Prolonged duration patients

(n = 194)

Univariate logistic regression

Multivariate logistic regressiona, c

Variables (total number (n))

n (%)

OR

95% CI

p value

OR

95% CI

p value

Sex

 Women (n = 326)

87 (26.7)

ref.

  

ref.

  

 Men (n = 380)

107 (28. 2)

1.08

0.77–1.5

0.66

1.05

0.74–1.49

0.78

Age: 10 years old increment

 

1.08

0.99–1.19

0.08

1.09

0.97–1.21

0.13

Comorbidity (n = 199)

68 (34.2)

1.57

1.01–2.24

0.01

   

 Diabetes (n = 51)

19 (37.3)

1.63

0.90–2.95

0.11

   

 Respiratory disease (n = 51)

19 (37.3)

1.63

0.90–2.95

0.11

   

Coronary heart disease (n = 32)

12 (37.5)

1.62

0.78–3.38

0.20

   

Immunodeficiency (n = 8)

4 (50.0)

2.67

0.66–10.8

0.17

   

Cancer (n = 11)

3 (27.3)

0.99

0.26–3.77

0.99

   

Hypertension (n = 10)

4 (40.0)

1.78

0.50–6.36

0.38

   

Others (n = 103)

36 (35.0)

1.51

0.97–2.36

0.07

   

Number of comorbidities

 0 (n = 511)

126 (24.7)

ref.

  

ref.

  

 1 (n = 134)

44 (32.8)

1.49

0.99–2.26

0.06

1.77

1.11–2.82

0.02

 2 + (n = 61)

24 (39.3)

1.98

1.14–3.44

0.02

2.47

1.32–4.61

0.01

Duration from illness onset to admission (hospitalized patients; n = 422)a

 

1.13

1.09–1.17

< 0.001

   

Symptoms

 Fever (n = 458)

120 (26.2)

0.83

0.59–1.18

0.3

0.96

0.65–1.42

0.85

 Cough (n = 377)

103 (27.3)

0.98

0.71–1.37

0.92

1.07

0.74–1.53

0.71

 Dyspnea (n = 164)

44 (26.8)

0.96

0.65–1.42

0.83

1.06

0.69–1.62

0.80

 Digestive symptoms (n = 108)

30 (27.8)

1.02

0.64–1.61

0.94

1.10

0.68–1.77

0.71

 Olfactory and taste disorders (n = 179)

50 (27.9)

1.03

0.71–1.51

0.88

1.03

0.69–1.55

0.88

 Fatigue (n = 269)

67 (24.9)

0.81

0.57–1.14

0.23

0.75

0.51–1.09

0.13

 Other (n = 367)

94 (25.6)

0.82

0.59–1.15

0.25

0.84

0.59–1.21

0.36

Location of recuperationb

 Non-hospital (n = 277)

94 (33.9)

ref.

  

ref.

  

 Hospital (n = 428)

100 (23.4)

0.59

0.42–0.83

0.002

0.44

0.29–0.65

< 0.001

  1. aSix cases (1.4%) had missing data on date of admission or location of recuperation. (n = 422)
  2. bOne case (0.1%) had missing data regarding the location of recuperation. (n = 705)
  3. cMultivariate logistic regression adjusted for sex, age (10 years old increment), number of comorbidities, symptoms (cough, dyspnea, digestive symptoms, olfactory and taste disorders, fatigue, other symptoms), and location of recuperation
  4. OR adjusted odds ratio, 95% CI 95% confidence interval, ref reference