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Table 1 Comparison of clinical characteristics between groups by duration of viral clearance

From: Factors associated with prolonged duration of viral clearance in non-severe SARS-CoV-2 patients in Osaka, Japan

 

Overall

Prolonged duration patients

Non-prolonged duration patients

p value

(n = 706)

(n = 194)

(n = 512)

Men, n (%)

380 (53.8)

107 (55.2)

273 (53.3)

0.66

Age, median [IQR]

45 [31–58]

47 [31–63]

45 [31–57]

0.1

Age categories

  < 30, n (%)

140 (19.8)

36 (18.6)

104 (20.3)

0.41

 30–39, n (%)

144 (20.4)

38 (19.6)

106 (20.7)

 

 40–49, n (%)

130 (18.4)

33 (17.0)

97 (19.0)

 

 50–59, n (%)

131 (18.6)

31 (16.0)

100 (19.5)

 

 60–69, n (%)

55 (7.8)

18 (9.3)

37 (7.2)

 

 70–79, n (%)

57 (8.1)

21 (10.8)

36 (7.0)

 

 80+, n (%)

49 (6.9)

17 (8.8)

32 (6.3)

 

Comorbidity, n (%)

199 (28.2)

68 (35.1)

131 (25.6)

0.01

 Diabetes, n (%)

51 (7.2)

19 (9.8)

32 (6.3)

0.1

 Respiratory disease, n (%)

51 (7.2)

19 (9.8)

32 (6.3)

0.1

 Coronary heart disease, n (%)

32 (4.5)

12 (6.2)

20 (3.9)

0.19

 Immunodeficiency, n (%)

8 (1.1)

4 (2.1)

4 (0.8)

0.15

 Cancer, n (%)

11 (1.6)

3 (1.6)

8 (1.6)

0.99

 Hypertension, n (%)

10 (1.4)

4 (2.1)

6 (1.2)

0.37

 Others, n (%)

103 (14.6)

36 (18.6)

67 (13.1)

0.07

Number of comorbidities, n (%)

 0

511 (72.4)

126 (65.0)

385 (75.2)

0.02

 1

134 (19.0)

44 (22.7)

90 (17.6)

 

 2+

61 (8.6)

24 (12.4)

37 (7.2)

 

Symptoms

 Fever, n (%)

458 (64.9)

120 (61.9)

338 (66.0)

0.3

 Cough, n (%)

377 (53.4)

103 (53.1)

274 (53.5)

0.92

 Dyspnea, n (%)

164 (23.2)

44 (22.7)

120 (23.4)

0.83

 Digestive symptoms, n (%)

108 (15.3)

30 (15.5)

78 (15.2)

0.94

 Olfactory and taste disorders, n (%)

179 (25.4)

50 (25.8)

129 (25.2)

0.88

 Fatigue, n (%)

269 (38.1)

67 (34.5)

202 (39.5)

0.23

 Others, n (%)

367 (52.0)

94 (48.5)

273 (53.3)

0.25

Radiological findings (chest examination), n (%)

236 (33.4)

65 (33.5)

171 (33.4)

0.95

 No findings, n (%)

76 (10.8)

22 (11.3)

54 (10.6)

 

 Missing, n (%)

394 (55.8)

107 (55.2)

287 (56.1)

 

Duration of viral clearance from symptom onset, median [IQR]

22 [17–29]

34 [31–39]

19 [15–23]

< 0.001

Location of recuperation at the time of the (first) PCR testa

 Hospital, n (%)

428 (60.7)

100 (51.6)

328 (64.2)

0.002

 Non-hospital, n (%)

277 (39.3)

94 (48.5)

183 (35.8)

 

Hospitalized patients

 Duration from illness onset to admissionb, median [IQR]

7 [5–10]

10 [7–16]

7 [4–9]

< 0.001

 Lengths of hospital stayc, median [IQR]

17 (12–23)

28 (22–33)

15 (10–19)

< 0.001

  1. aOne case (0.1%) had missing data regarding the location of recuperation (n = 705)
  2. bSix cases (0.8%) had missing data on date of admission (overall n = 422; prolonged duration patients n = 95; non-prolonged duration patients n = 327)
  3. cEight cases (1.1%) of hospitalized patients had missing data on date of admission and/or discharge (overall n = 420; prolonged duration patients n = 93; non-prolonged duration patients n = 327)