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Table 1 Concentrations of chemical compounds detected in the mainstream smoke of HTPs using Tenax GR cartridge and CFP (μg/stick) (n = 3). n.d. means not determined

From: Analysis of furans and pyridines from new generation heated tobacco product in Japan

Compound (μg/stick)

IQOS

glo

ploom S

3R4F

Regular

Menthol

Berry boost

Dark fresh

Regular taste

Menthol purple

Furans

 Furfural

98 ± 16

1.7 ± 0.17

170 ± 8.4

180 ± 16

11 ± 0.49

2.0 ± 0.16

86 ± 22

 2-Furanmethanol

15 ± 5.1

0.11 ± 0.010

34 ± 4.5

46 ± 5.6

2.4 ± 0.18

2.1 ± 0.11

4.2 ± 0.74

 2(5H)-Furanone

3.0 ± 0.98

n.d.

12 ± 1.8

14 ± 1.1

1.4 ± 0.10

n.d.

6.6 ± 0.91

 5-Methylfurfural

33 ± 6.8

0.35 ± 0.030

55 ± 4.3

70 ± 8.2

2.7 ± 0.17

1.0 ± 0.07

12 ± 2.3

Pyridines

 Pyridine

5.2 ± 0.84

6.1 ± 0.85

2.7 ± 0.33

3.1 ± 0.20

0.75 ± 0.020

0.41 ± 0.02

33 ± 4.1

 2,6-Dimethylpyridine

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

1.5 ± 0.28

 2,5-Dimethylpyrazine

0.78 ± 0.013

0.010 ± 0.0

0.42 ± 0.030

0.53 ± 0.0

0.73 ± 0.020

0.22± 0.03

4.0 ± 0.62

 2-Ethenylpyridine

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

0.59 ± 0.10

 3-Ethylpyridine

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

1.4 ± 0.93

 4-Ethenylpyridine

1.5 ± 0.30

0.67 ± 0.14

2.5 ± 0.26

0.94 ± 0.030

0.65 ± 0.010

1.1 ± 1.0

6.3 ± 1.4

 3-Ethenylpyridine

0.50 ± 0.13

n.d.

0.15 ± 0.010

0.55 ± 0.080

0.31 ± 0.020

0.19 ± 0.060

3.7 ± 0.36

 2,3,5-Trimethylpyrazine

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

Additives

 Benzyl alcohol

0.30 ± 0.080

0.080 ± 0.010

0.62 ± 0.12

1.0 ± 0.050

0.22 ± 0.020

n.d.

4.2 ± 0.31

 Linalool

0.52 ± 0.36

0.020 ± 0.0

13 ± 1.4

0.05 ± 0.010

0.020 ± 0.0

3.4 ± 0.18

0.12 ± 0.11

 Menthol

2.5 ± 0.22

1100 ± 64

1700 ± 200

1500 ± 41

0.93 ± 0.18

720 ± 12

4.5 ± 3.9

 4-Ethyl guaiacol

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

0.79 ± 0.090

 Eugenol

n.d.

n.d.

n.d.

n.d.

n.d.

0.10 ± 0.01

n.d.

Others

 Nicotine (mg/stick)

1.2 ± 0.059

1.3 ± 0.082

1.0 ± 0.0037

1.2 ± 0.022

0.7 ± 0.0

0.6 ± 0.0

1.8 ± 0.0

 Water (mg/stick)

27 ± 7.7

26 ± 4.4

15 ± 1.0

17 ± 1.7

16 ± 0.3

18 ± 0.6

10 ± 2.3

 Tar (mg/stick)

13 ± 3.0

10 ± 5.3

22 ± 2.4

18 ± 2.5

13 ± 8.5

12 ± 9.8

27 ± 1.8

 Total (mg/stick)

42 ± 1.3

38 ± 0.42

38 ± 2.3

37 ± 2.8

30 ± 3.3

31 ± 3.3

49 ± 3.7