Environmental Health and Preventive Medicine

Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for reduced handgrips strength by atherosclerosis in relation to rs17081935 genotypes

From: Association between height-related polymorphism rs17081935 and reduced handgrip strength in relation to status of atherosclerosis: a cross-sectional study

	Atherosclerosis		p	[p]^b
	( −)	( +)	p	[p]^b
CC-homozygotes
No. of participants	452	128
No. of case (%)	75 (16.6)	46 (35.9)
Erythrocyte, × 10⁴/μL	447 ± 40	438 ± 41	0.023
Model 1	Ref	2.13 (1.34, 3.40)	0.002	0.962
Model 2	Ref	2.15 (1.35, 3.45)	0.001	0.839
Model 3	Ref	2.25 (1.39, 3.63)	< 0.001	0.501
Model 4	Ref	2.27 (1.41, 3.67)	< 0.001	0.240
CT-heterozygotes
No. of participants	475	129
No. of case (%)	101 (21.3)	30 (23.3)
Erythrocyte, × 10⁴/μL	441 ± 40	446 ± 46	0.238
Model 1	Ref	0.77 (0.47, 1.27)	0.299	0.529
Model 2	Ref	0.75 (0.46, 1.25)	0.271	0.742
Model 3	Ref	0.79 (0.47, 1.34)	0.379	0.832
Model 4	Ref	0.84 (0.50, 1.41)	0.505	0.734
TT-homozygotes
No. of participants	149	41
No. of case (%)	26 (17.4)	7 (17.1)
Erythrocyte, × 10⁴/μL	441 ± 44	450 ± 37	0.271
Model 1	Ref	0.60 (0.22, 1.63)	0.320	0.433
Model 2	Ref	0.55 (0.19, 1.58)	0.269	0.299
Model 3	Ref	0.74 (0.26, 2.16)	0.586	0.321
Model 4	Ref	0.77 (0.27, 2.15)	0.614	0.090

^b: P for good for fit test evaluated by the Hosmer–Lemeshow test. Ref: reference. Model 1, adjusted only for sex and age. Model 2, adjusted further for drinking status (non, often, daily), smoking status (never, former, current), BMI status (< 18.0 kg/m², 18.0–24.9 kg/m², and 25 kg/m² ≤), hypertension, dyslipidemia, diabetes. Model 3, further adjusted for height. Model 4, adjusted only for sex, age, height, and renal function (< 60 mL/min/1.73m², 60–89 mL/min/1.73m², 90 ml/min/1.73 m² ≤)

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