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Table 3 Odds ratios (ORs) and 95% confidence intervals (CIs) for reduced handgrips strength in relation to rs17081935 genotypes by atherosclerosis

From: Association between height-related polymorphism rs17081935 and reduced handgrip strength in relation to status of atherosclerosis: a cross-sectional study

  rs17081935 genotypes p Minor allele (T) [p]b
(C/C) (C/T) (T/T)
Atherosclerosis ( −)
 No. of participants 452 475 149    
 No. of case (%) 75 (16.6) 101 (21.3) 26 (17.4)    
 Heighta (standard error) 155.0 (0.3) 155.0 (0.3) 155.9 (0.5) 0.186   
 Erythrocyte, × 104/μL 447 ± 40 441 ± 40 441 ± 44 0.098   
 Model 1 Ref 1.38 (0.97, 1.95) 1.08 (0.64, 1.81) 0.353 1.12 (0.89, 1.41) 0.057
 Model 2 Ref 1.38 (0.97, 1.96) 1.08 (0.64, 1.82) 0.350 1.12 (0.89, 1.41) 0.786
 Model 3 Ref 1.34 (0.94, 1.92) 1.11 (0.65, 1.90) 0.343 1.13 (0.86, 1.43) 0.424
 Model 4 Ref 1.35 (0.94, 1.93) 1.12 (0.65, 1.91) 0.329 1.13 (0.89, 1.44) 0.402
Atherosclerosis ( +)
 No. of participants 128 129 41    
 No. of case (%) 46 (35.9) 30 (23.3) 7 (17.1)    
 Heighta (standard error)  156.2 (0.5) 156.3 (0.5) 158.2 (0.9) 0.116   
 Erythrocyte, × 104/μL 438 ± 41 446 ± 46 450 ± 37 0.158   
 Model 1 Ref 0.51 (0.29, 0.91) 0.33 (0.13, 0.84) 0.005 0.55 (0.37, 0.83) 0.379
 Model 2 Ref 0.47 (0.26, 0.85) 0.32 (0.12, 0.81) 0.003 0.53 (0.34, 0.81) 0.588
 Model 3 Ref 0.46 (0.25, 0.84) 0.38 (0.15, 0.99) 0.008 0.55 (0.36, 0.86) 0.712
 Model 4 Ref 0.48 (0.27, 0.88) 0.40 (0.16, 1.01) 0.010 0.57 (0.37, 0.88) 0.951
  1. a Sex and age adjusted values of height. bP for good for fit test evaluated by the Hosmer–Lemeshow test. Ref: reference. Model 1, adjusted only for sex and age. Model 2, adjusted further for drinking status (non, often, daily), smoking status (never, former, current), BMI status (< 18.0 kg/m2, 18.0–24.9 kg/m2, and 25 kg/m2 ≤), hypertension, dyslipidemia, diabetes. Model 3, further adjusted for height. Model 4, adjusted only for sex, age, height, and renal function (< 60 mL/min/1.73 m2, 60–89 mL/min/1.73m2, 90 ml/min/1.73m2 ≤)