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Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for diastolic hypertension in relation to handgrip strength stratified by circulating CD34-positive cell count

From: Associations between handgrip strength and hypertension in relation to circulating CD34-positive cell levels among Japanese older men: a cross-sectional study

 

Handgrip strength levels

p for trend

p (goodness of fit test)

1 SD increment of handgrip strength (kg)

T1 (low)

T2

T3 (high)

High CD34-positive cell count (≥ 0.96 cells/μL)

 No. of participants

37

49

43

   

 No. of cases (%)

10 (27.0)

19 (38.8)

21 (48.8)

   

 Age-adjusted ORs

1.00

1.69 (0.67, 4.26)

2.48 (0.96, 6.39)

0.060

0.934

1.71 (1.11, 2.64)

 Multivariable ORs

1.00

1.61 (0.59, 4.36)

2.58 (0.93, 7.12)

0.066

0.416

1.77 (1.11, 2.82)

Low CD34-positive cell count (< 0.96 cells/μL)

 No. of participants

49

39

40

   

 No. of cases (%)

15 (30.6)

9 (23.1)

18 (45.0)

   

 Age-adjusted ORs

1.00

0.62 (0.23, 1.68)

1.65 (0.66, 4.15)

0.280

0.854

1.07 (0.74, 1.55)

 Multivariable ORs

1.00

0.52 (0.17, 1.60)

1.17 (0.39, 3.54)

0.745

0.891

0.99 (0.64, 1.55)

 

Interaction*

 

p

 

Age-adjusted model

1.58 (0.91, 2.76)

0.105

Multivariable model

1.82 (1.03, 3.24)

0.041

  1. Diastolic hypertension is defined as diastolic blood pressure ≥ 90 mmHg. Multivariable ORs: adjusted further for age and BMI, anti-hypertensive medication, HDLc, TG, γ-GTP, WBC, HbA1c, and GFR. BMI body mass index, HDLc HDL-cholesterol, TG triglycerides, HbA1c hemoglobin A1c, γ-GTP γ-glutamyltranspeptidase, WBC white blood cell, GFR glomerular filtration rate. Handgrip strength tertiles are as follows: < 37.0 kg for T1, 37.0–41.9 kg for T2, and ≥ 42.0 kg for T3. *The effect of interaction between circulating CD34-positive cell levels and handgrip strength (1 SD increment: 6.0kg) on diastolic hypertension