From: Hokkaido birth cohort study on environment and children’s health: cohort profile 2021
Hokkaido cohort | Sapporo cohort | |
---|---|---|
Recruitment | 2003-2012 | 2002-2005 |
Participates | 20,926 (37 clinics/hospitals) | 514 (1 hospital) |
Objectives | 1. To find the effects of perinatal environmental factors, especially chemical exposure at low levels, on child health, including congenital anomalies, growth retardation, birth size, allergies, neurodevelopment, growth, and puberty. 2. To evaluate the prevalence of allergic diseases, developmental and neurobehavioral disorders. 3. To identify a high-risk group classified by genetic susceptibility (SNPs) and investigate trans-generational epigenetic effects of environmental chemicals. 4. To provide scientific evidence for health policies based on human epidemiological data. |