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Table 1 Summary of the birth cohort study

From: Hokkaido birth cohort study on environment and children’s health: cohort profile 2021

 

Hokkaido cohort

Sapporo cohort

Recruitment

2003-2012

2002-2005

Participates

20,926

(37 clinics/hospitals)

514

(1 hospital)

Objectives

1. To find the effects of perinatal environmental factors, especially chemical exposure at low levels, on child health, including congenital anomalies, growth retardation, birth size, allergies, neurodevelopment, growth, and puberty.

2. To evaluate the prevalence of allergic diseases, developmental and neurobehavioral disorders.

3. To identify a high-risk group classified by genetic susceptibility (SNPs) and investigate trans-generational epigenetic effects of environmental chemicals.

4. To provide scientific evidence for health policies based on human epidemiological data.