Table 2 Age- and sex-adjusted and multivariable-adjusted hazard ratios for the development of cardiovascular disease and its subtypes according to urinary NT-proBNP levels

 ≤ 19

1354

38

1.00 (reference)

1.00 (reference)

 20–26

1105

59

1.25 (0.82–1.90)

0.30

1.30 (0.86–1.99)

0.22

 27–42

369

34

1.49 (0.90–2.47)

0.12

1.51 (0.91–2.51)

0.11

 ≥ 43

232

39

2.41 (1.44–4.04)

< 0.001

2.07 (1.20–3.56)

0.009

 P for trend

< 0.001

0.009

 ≤ 19

1354

23

1.00 (reference)

1.00 (reference)

 20–26

1105

26

0.98 (0.55–1.75)

0.93

1.01 (0.56–1.82)

0.97

 27–42

369

18

1.54 (0.77–3.04)

0.22

1.52 (0.76–3.06)

0.24

 ≥ 43

232

11

1.33 (0.59–3.00)

0.49

1.09 (0.45–2.63)

0.85

 P for trend

0.28

0.52

 ≤ 19

1354

15

1.00 (reference)

1.00 (reference)

 20–26

1105

34

1.73 (0.93–3.21)

0.09

1.76 (0.95–3.29)

0.07

 27–42

369

17

1.67 (0.79–3.51)

0.18

1.66 (0.79–3.51)

0.18

 ≥ 43

232

28

3.81 (1.86–7.80)

< 0.001

3.24 (1.54–6.85)

0.002

 P for trend

< 0.001

0.004