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Table 1 Demographic characteristics and clinical outcomes in the study population

From: Maternal metal concentration during gestation and pediatric morbidity in children: an exploratory analysis

Subjects’ characteristics

Study population

(N = 111 newborns)

(N = 111 deliveries)

Demography

 Maternal age, years

  Mean ± SD (n)

28.1 ± 6.3 (110)

  Median

26.9

  Min; max

18.4; 41.7

 Parity, % (n/N)

  1

27.3 (30/110)

  2–5

42.7 (47/110)

  6+

30.0 (33/110)

 Gestational age, weeks

  Mean ± SD (n)

39.4 ± 1.8 (111)

  Median

39.0

  Min; max

32.0; 44.0

 Infant weight, grams

  Mean ± SD (n)

3287.3 ± 457.5 (111)

  Median

3345.0

  Min; max

1725.0; 4165.0

 Small-to-gestational age (SGA), % (n/N)

6.4 (7/109)

 Infant male gender, % (n/N)

54.1 (60/111)

 Children’s age at follow-up, years

  Mean ± SD (n)

6.1 ± 0.3 (111)

  Median

6.1

  Min; max

5.4; 6.9

Clinical outcomes,

 Preterm delivery, % (n/N)

10.8 (12/111)

 Malformations diagnosed at birth or follow-up, % (n/N)

7.2 (8/111)

 Malformations’ severity, % (n/N)

 

  Major

1.5 (5/111)

  Minor

2.7 (3/111)

 Asthma morbidity, % (n/N)

  Reported as treated

69.4 (77/111)

  Diagnosed

51.4 (57/111)

 Cardiovascular morbidity, % (n/N)

  Reported as treated

10.8 (12/111)

  Diagnosed

0 (0/111)

 Behavioral conditionsa, % (n/N)

  Reported as treated

6.3 (7/111)

  Diagnosed

0.9 (1/111)

 Obesity, % (n/N)

  Reported as treated

5.4 (6/111)

  Diagnosed

5.4 (6/111)

 Burden of disease, % (n/N)

  0

26.1 (29/111)

  1–2

69.4 (77/111)

  3–4

3.6 (4/111)

  5–6

0.9 (1/111)

  1. aPatients who visited a developmental outpatient clinic at the ages 0.5–3 years (in all 6 patients) and/or diagnosed with a behavioral disorder (1 patient—autism and developmental delay).