Table 4 Associations between TAR/TLR and cardiometabolic variables after adjusting for potential confounders
Total subjects, N = 597 | Medications for hypertension, dyslipidemia, or diabetes | |||||||
|---|---|---|---|---|---|---|---|---|
Users, N = 347 | Non-users, N = 250 | Non-overweight non-users, N = 199 | ||||||
Beta | P | Beta | P | Beta | P | Beta | P | |
TAR | ||||||||
Systolic blood pressure | 0.03 | ns | 0.04 | ns | 0.03 | ns | − 0.02 | ns |
Diastolic blood pressure | 0.00 | ns | 0.04 | ns | − 0.02 | ns | − 0.09 | ns |
LDL cholesterol | 0.09 | 0.04 | 0.04 | ns | 0.19 | < 0.01 | 0.22 | < 0.01 |
HDL cholesterol | − 0.25 | < 0.01 | − 0.25 | < 0.01 | − 0.22 | < 0.01 | − 0.20 | < 0.01 |
Total cholesterol | 0.02 | ns | − 0.02 | ns | 0.13 | ns | 0.16 | ns |
Triglyceride | 0.32 | < 0.01 | 0.33 | < 0.01 | 0.28 | < 0.01 | 0.27 | < 0.01 |
Hemoglobin A1c | 0.17 | < 0.01 | 0.12 | 0.04 | 0.18 | 0.02 | 0.15 | ns |
Fasting serum insulin | 0.25 | < 0.01 | 0.23 | < 0.01 | 0.23 | < 0.01 | 0.19 | < 0.01 |
Fasting plasma glucose | 0.17 | < 0.01 | 0.12 | 0.03 | 0.17 | 0.02 | 0.12 | ns |
HOMA− IR | 0.25 | < 0.01 | 0.23 | < 0.01 | 0.25 | < 0.01 | 0.20 | < 0.01 |
TLR | ||||||||
Systolic blood pressure | 0.03 | ns | 0.04 | ns | 0.03 | ns | − 0.02 | ns |
Diastolic blood pressure | − 0.01 | ns | 0.03 | ns | − 0.03 | ns | − 0.10 | ns |
LDL cholesterol | 0.08 | ns | 0.02 | ns | 0.20 | < 0.01 | 0.23 | < 0.01 |
HDL cholesterol | − 0.24 | < 0.01 | − 0.25 | < 0.01 | − 0.20 | < 0.01 | − 0.18 | 0.01 |
Total cholesterol | 0.02 | ns | − 0.03 | ns | 0.16 | 0.03 | 0.18 | 0.03 |
Triglyceride | 0.32 | < 0.01 | 0.32 | < 0.01 | 0.29 | < 0.01 | 0.28 | < 0.01 |
Hemoglobin A1c | 0.17 | < 0.01 | 0.12 | 0.03 | 0.19 | < 0.01 | 0.15 | ns |
Fasting serum insulin | 0.25 | < 0.01 | 0.24 | < 0.01 | 0.21 | < 0.01 | 0.16 | 0.03 |
Fasting plasma glucose | 0.17 | < 0.01 | 0.12 | 0.03 | 0.17 | 0.02 | 0.09 | ns |
HOMA− IR | 0.25 | < 0.01 | 0.24 | < 0.01 | 0.23 | < 0.01 | 0.16 | 0.03 |