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Table 3 Effect of chronic exposure of different concentrations of BPS (0.5 μg/L, 5 μg/L, and 50 μg/L) on plasma testosterone and estradiol concentrations in male rats

From: Chronic exposure of bisphenol S (BPS) affect hypothalamic-pituitary-testicular activities in adult male rats: possible in estrogenic mode of action

   Hormones  
Groups Testosterone (ng/ml) Estradiol (pg/ml) LH (ng/ml) FSH (mIU/ml)
Control 12.36 ± 0.38 2.71 ± 0.24 1.84 ± 0.10 0.79 ± 0.04
BPS 0.5 μg/L 11.77 ± 0.37 3.52 ± 0.31 1.54 ± 0.12 0.68 ± 0.09
BPS 5 μg/L 10.56 ± 0.52** 3.69 ± 0.32* 1.55 ± 0.05 0.57 ± 0.07
BPS 50 μg/L 9.76 ± 0.25*** 4.11 ± 0.13** 1.45 ± 0.10* 0.48 ± 0.03*
  1. Values are presented as mean ± SEM (n = 8)
  2. *, **, *** indicate significance at P < 0.05, P < 0.01, and P < 0.001 vs control