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Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to status of HTLV-1 infection by platelet levels

From: Possible mechanisms underlying the association between human T-cell leukemia virus type 1 (HTLV-1) and hypertension in elderly Japanese population

 

Platelet levels

Interaction

The lowest (T1)

Higher (T2 + T3)

HTLV-1 infection

p

HTLV-1 infection

p

(−)

(+)

(−)

(+)

Total subjects

 No. of participants

791

210

 

1618

370

  

 No. of cases (%)

492 (62.2)

137 (65.2)

 

1110 (68.6)

231 (62.4)

  

 Model 1

1.00

1.06 (0.77, 1.47)

0.721

1.00

0.68 (0.53, 0.87)

0.002

0.037

 Model 2

1.00

1.01 (0.72, 1.42)

0.945

1.00

0.64 (0.50, 0.82)

< 0.001

0.004

  1. Model 1 adjusted only for sex and age, Model 2 adjusted further for sex and age, body mass index, triglycerides, HDL-cholesterol, HbA1C, white blood cell, and γ-GTP. Platelet level: The lowest (T1) is < 19.3 × 104/μL for men and < 20.7 × 104/μL for women. Higher (T2 × T3) is ≥ 19.3 × 104/μL for men and ≥ 20.7 × 104/μL for women