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Table 5 Multiple linear regression showing DLEC1 promoter methylation in relation to regular exercise habits and PM2.5 quartiles

From: PM2.5 exposure and DLEC1 promoter methylation in Taiwan Biobank participants

Variables

β(× 10−3)

p value

Regular outdoor exercise, PM2.5 (reference: No regular outdoor exercise, PM2.5 ≥ 38.73)

 No regular outdoor exercise, 31.82 ≤ PM2.5 < 38.73

2.150

0.198

 No regular outdoor exercise, 27.37 ≤ PM2.5 < 31.82

0.136

0.934

 No regular outdoor exercise, PM2.5 < 27.37

− 0.808

0.634

 Regular outdoor exercise, PM2.5 ≥ 38.73

1.310

0.444

 Regular outdoor exercise, 31.82 ≤ PM2.5 < 38.73

0.570

0.750

 Regular outdoor exercise, 27.37 ≤ PM2.5 < 31.82

0.410

0.827

 Regular outdoor exercise, PM2.5 < 27.37

− 5.160

0.007

 SO2

0.209

0.544

 CO

− 6.270

0.379

 O3

− 0.010

0.964

 NOX

0.038

0.759

Sex (reference: Women)

 Men

0.652

0.490

 Age

− 0.207

< 0.001

Cigarette smoking (reference: Never)

 Former

1.470

0.274

 Current

2.340

0.123

Alcohol drinking (reference: Never)

 Former

− 3.390

0.174

 Current

1.690

0.336

Betel nut chewing (reference: Never)

 Former

− 1.820

0.459

 Current

− 4.270

0.145

BMI (reference: Normal)

 Underweight

− 1.070

0.620

 Overweight

− 0.264

0.791

 Obesity

1.620

0.143

Secondhand smoke exposure (reference: No)

 Yes

− 0.309

0.826

  1. DLEC1 Deleted in lung and esophageal cancer 1, PM Particulate matter with diameter less than 2.5 microns, SO2 Sulfur dioxide, CO Carbon monoxide, O3 Ozone, NOx Nitrogen oxides, BMI Body mass index