Table 1 Effects of different concentrations of resveratrol on platelet aggregation (upper lines) and Ca2+ entry into platelets (lower lines) induced by thrombin, thapsigargin, and OAG
From: Resveratrol inhibits Ca2+ signals and aggregation of platelets
Resveratrol (μM) | 0 | 3.125 | 6.25 | 12.5 | 25 | 50 |
|---|---|---|---|---|---|---|
Thrombin | ||||||
Aggregation (%) | 81.83 (4.02) | 73.38 (3.46) | 66.25 (5.50)* | 58.33 (12.09)** | 40.8 (6.53)** | 21.75 (9.57)** |
Ca2+ entry (nM) | 125.34 (29.13) | 104.73 (19.32) | 101.63 (25.94) | 92.59 (18.37)* | 83.65 (4.98)** | 63.52 (11.55)** |
Thapsigargin | ||||||
Aggregation (%) | 69.88 (3.08) | 71.00 (5.18) | 63.86 (7.40)** | 49.17 (10.61)** | 38.00 (9.17)** | 20.50 (8.34)** |
Ca2+ entry (nM) | 604.78 (128.07) | 465.95 (126.16) | 396.62 (129.83)** | 395.69 (70.90)** | 351.37 (37.91)** | 320.73 (68.26)** |
OAG | ||||||
Aggregation (%) | 76.60 (4.40) | 75.00 (3.00) | 77.33 (2.31) | 74.00 (4.42) | 70.50 (3.41) | 67.00 (6.90) |
Ca2+ entry (nM) | 93.31 (16.64) | 90.57 (6.92) | 95.54 (5.45) | 88.64 (12.48) | 79.67 (11.28) | 77.19 (12.11) |