Environmental factors involved in SARS-CoV-2 transmission: effect and role of indoor environmental quality in the strategy for COVID-19 infection control

Table 1 Persistence of coronaviruses in aerosols at different temperatures and relative humidity

Virus	Temperature (°C)	RH (%)	Virus load	Aerosolized time	Survival rate (%)	Decay rate (%/min)	Half-life (h)	Reference
SARS-CoV-2	21–23	65	10^3.5 TCID₅₀/L air	3 h	15.8	NR	1.09	van Doremalen et al. [28]
SARS-CoV-1	21–23	65	10^4.3 TCID₅₀/L air	3 h	15.8	NR	1.18	van Doremalen et al. [28]
SARS-CoV-2	19–22	40–60	10⁶ TCID₅₀/mL aerosol of tissue culture media	90 min	NR	0.91	1.25	Smither et al. [29]
SARS-CoV-2	19–22	68–88	10⁶ TCID₅₀/mL aerosol of tissue culture media	90 min	NR	1.59	NR	Smither et al. [29]
SARS-CoV-2	19–22	40–60	10⁶ TCID₅₀/mL aerosol of artificial saliva	90 min	NR	2.27	0.5	Smither et al. [29]
SARS-CoV-2	19–22	68–88	10⁶ TCID₅₀/mL aerosol of artificial saliva	90 min	NR	0.40	2.95	Smither et al. [29]

Abbreviations: NR not reported, RH relative humidity, SARS-CoV severe acute respiratory syndrome coronavirus, TCID₅₀ tissue culture infectious dose 50

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