Table 4 Risks for fetal CHD in different maternal hair cobalt concentrations
Group | Total hair Co | Hair low n = 197 (< 0.0161 ng/mg) | Hair medium n = 199 (0.0161 ng/mL–0.0435 ng/mg) | Hair high n = 197 (> 0.0435 ng/mg) |
|---|---|---|---|---|
Control (n) | 325 | 153 | 87 | 85 |
All cases (n) | 268 | 44 | 112 | 112 |
cOR | 1.761*** | Reference | 4.476*** | 4.582*** |
aOR | 0.090 | Reference | 3.035*** | 1.995* |
95% CI | 0.004–2.264 |  | 1.809–5.092 | 1.116–3.569 |
Case with septal defects (n) | 182 | 27 | 78 | 77 |
 cOR | 1.652 | Reference | 5.080*** | 5.133*** |
 aOR | 0.148 | Reference | 4.183*** | 2.544** |
 95% CI | 0.006–3.815 |  | 2.283–7.664 | 1.289–5.021 |
Case with conotruncal defects (n) | 133 | 21 | 59 | 53 |
 cOR | 1.528 | Reference | 4.941*** | 4.543*** |
 aOR | 0.001 | Reference | 3.133*** | 1.885 |
 95% CI | 0.001–1.865 |  | 1.628–6.029 | 0.899–3.952 |
Case with right ventricular outflow tract obstruction (n) | 123 | 16 | 54 | 53 |
 cOR | 1.627** | Reference | 5.935*** | 5.962*** |
 aOR | 0.016 | Reference | 3.657*** | 2.717*** |
 95% CI | 0.001–7.969 |  | 1.805–7.408 | 1.251–5.902 |
Case with left ventricular outflow tract obstruction (n) | 41 | 5 | 20 | 16 |
 cOR | 1.679** | Reference | 7.034*** | 5.760** |
 aOR | 0.553 | Reference | 4.168*** | 2.701 |
 95% CI | 0.020–15.498 |  | 1.254–13.854 | 0.719–10.150 |
Case with anomalous pulmonary venous return (n) | 42 | 8 | 19 | 15 |
 cOR | 1.483* | Reference | 4.177** | 3.375** |
 aOR | 0.003 | Reference | 2.585 | 0.969 |
 95% CI | 0.001–138.136 |  | 0.991–6.746 | 0.296–3.174 |
Case with other heart defects (n) | 48 | 10 | 18 | 20 |
 cOR | 1.521** | Reference | 3.166** | 3.600** |
 aOR | 0.004 | Reference | 1.330 | 1.255 |
 95% CI | 0.001–156.466 |  | 0.500–3.536 | 0.424–3.710 |