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Table 1 Clinical features of patients

From: Identification by TCGA database search of five genes that are aberrantly expressed and involved in hepatocellular carcinoma potentially via DNA methylation changes

  

Number of patients (rates)

Non-tumor tissue

HCC

Races

White

26 (63.4%)

184 (49.6%)

American Indian or Alaska native

0 (0%)

2 (0.5%)

Black or African American

7 (17.1%)

17 (4.6%)

Asian

5 (12.2%)

158 (42.6%)

Not reported

3 (7.3%)

10 (2.7%)

Age (year)

 

20–78

16–85

Gender

Male

18 (43.9%)

250 (67.4%)

Female

23 (56.1%)

121 (32.6%)

History of HCC factor

None

14 (34.1%)

91 (24.5%)

Alcohol consumption

6 (14.6%)

68 (18.3%)

Hepatitis B

6 (14.6%)

75 (20.2%)

Hepatitis C

5 (12.2%)

32 (8.6%)

Non-alcoholic fatty liver disease

2 (4.9%)

11 (3.0%)

Hemochromatosis

0 (0%)

5 (1.3%)

Complex

1 (2.4%)

58 (15.6%)

Other

4 (9.8%)

12 (3.2%)

No data

3 (7.3%)

19 (5.1%)

Histologic grade

G1

5 (12.2%)

55 (14.8%)

G2

20 (48.8%)

177 (47.7%)

G3

14 (34.1%)

122 (32.9%)

G4

2 (4.9%)

12 (3.2%)

No data

0 (0%)

5 (1.3%)

AJCC TNM staging systema (presence or absence of distant metastasis)

M0

27 (65.9%)

266 (71.7%)

M1

1 (2.4%)

4 (1.1%)

MXb

13 (31.7%)

101 (27.2%)

AJCC TNM staging system (lymph node involvement)

N0

25 (61.0%)

252 (67.9%)

N1

1 (2.4%)

4 (1.1%)

NXc

14 (34.1%)

114 (30.7%)

No data

1 (2.4%)

1 (0.3%)

AJCC TNM staging system (tumor size and extent of tumors)

T1

19 (46.3%)

181 (48.8%)

T2

10 (24.4%)

94 (25.3%)

T3

9 (22.0%)

80 (21.6%)

T4

3 (7.3%)

13 (3.5%)

Otherd

0 (0%)

3 (0.8%)

AJCC pathological stage

Stage I

17 (41.5%)

171 (46.1%)

Stage II

7 (17.1%)

86 (23.2%)

Stage III

8 (19.5%)

85 (22.9%)

Stage IV

1 (2.4%)

5 (1.3%)

No datae

8 (19.5%)

22 (5.9%)

Othere

0 (0%)

2 (0.5%)

  1. aAJCC TNM staging system: tumor-node-metastasis staging system which was creased and is updated by the American Joint Committee on Cancer (AJCC) (https://www.cancer.gov/about-cancer/diagnosis-staging/staging)
  2. bMX: metastasis cannot be measured
  3. cNX: cancer in nearby lymph nodes cannot be measured
  4. dOther includes TX (main tumor cannot be measured), [discrepancy], and no data
  5. eOther includes [discrepancy]
  6. No data, data are not available