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Fig. 3 | Environmental Health and Preventive Medicine

Fig. 3

From: Identification by TCGA database search of five genes that are aberrantly expressed and involved in hepatocellular carcinoma potentially via DNA methylation changes

Fig. 3

CpGis of FANCB, KIF15, KIF4A, ERCC6L, and UBE2C were hypomethylated in HCC tissues. a Mean methylation β values were calculated using data from 74 HCC tissues highly expressing each gene and data from 41 non-tumor tissues. Wilcoxon rank sum test was conducted using an online program and p value < 0.05 was considered statistically significant. The β values of CpG in CpGi of FANCB (b), KIF15 (c), KIF4A (d), ERCC6L (e), and UBE2C (f) in 74 HCC tissues highly expressing each gene were compared with the β values of 41 non-tumor tissues. Statistical significance between the two groups was analyzed by Student’ s t test. *. **. *** Significantly different at p < 0.05, p < 0.01, and p < 0.001, respectively

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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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