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Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for advanced periodontitis in relation to human T cell leukemia virus type-1 (HTLV-1) infections by status of atherosclerosis

From: Association between human T cell leukemia virus type-1 (HTLV-1) infection and advanced periodontitis in relation to atherosclerosis among elderly Japanese: a cross-sectional study

 AtherosclerosisInteraction
(−)(+) 
HTLV-1 infectionpHTLV-1 infectionpp
(−)(+)(−)(+)
No. of subjects512100 23263  
No. of case (%)108 (21.1)15 (15.0) 52 (22.4)22 (34.9)  
Model 11.000.64 (0.35, 1.15)0.1351.002.02 (1.09, 3.73)0.0260.015
Model 21.000.62 (0.34, 1.13)0.1161.002.00 (1.05, 3.78)0.0340.011
Model 31.000.61 (0.34, 1.12)0.1131.002.01 (1.06, 3.81)0.0330.013
  1. Advanced periodontitis is defined as periodontal pocket ≥ 6.0 mm. Atherosclerosis is defined as carotid intima-media thickness (CIMT) ≥ 1.1 mm. Model 1: adjusted only for sex and age. Model 2: adjusted further for smoking status (never, former, current), number remaining teeth, status of decayed teeth (presence, absence), body mass index (BMI), HDL-cholesterol, triglycerides, hemoglobin A1c (HbA1c), reticulocyte count, and CIMT. Model 3: adjusted further for antihyerlipidemic medication use (yes, no) and glucose-lowering medication use (yes, no)