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Table 4 Protective effect of C. album extract against HgCl2-induced alterations in DSP and DNA damage

From: Ameliorating potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in testes of Sprague Dawley rats

Parameters

Control

Mercury

Mercury + vit C

Mercury + C. album

C. album alone

DSP parameters

 DSP/100 mg testis (105)

17.05 ± 1.14

6.20 ± 1.07a***

17.60 ± 0.71b***

15.40 ± 0.58b***

17.67 ± 1.19+++

 DSP efficiency (105)

225 ± 7.88

120 ± 4.93a***

256.60 ± 7.45a*b***

254.60 ± 8.09a*b***

230 ± 6.99++++

Comet assay parameters

 Comet head length (μm)

91.40 ± 9.09

149.40 ± 7.38a***

125 ± 8.62a*

119.20 ± 7.32

92.01 ± 8.49+++

 Comet tail length (μm)

16.80 ± 2.16

30.20 ± 1.47a*

26.20 ± 3.46

22.80 ± 3.41

16.20 ± 2.36+

 %DNA in head

91.51 ± 0.83

89.47 ± 1.87

91.04 ± 2.01

94.58 ± 1.26

92.11 ± 0.76

 %DNA in tail

5.32 ± 0.37

8.01 ± 0.33a*

8.17 ± 0.95a*

9.56 ± 0.24a***

5.30 ± 0.34+

 Tail movement

1.05 ± 0.30

2.31 ± 0.31

1.95 ± 0.36

1.09 ± 0.39

1.01 ± 0.27

  1. Values are expressed as mean ± SEM; “*,” “**,” and “***” indicating significance level from control group at p < 0.05, p < 0.01, and p < 0.001 probability levels. “+,” “++,” and “+++” indicate significance level from Mercury group at p < 0.05, p < 0.01, and p < 0.001 probability levels, whereas “,” “−−,” and “−−−” indicate significance from Mercury + vit C group at p < 0.05, p < 0.01, and p < 0.001 probability levels, respectively