Table 4 Oral subchronically administered rats with Bisphenol F (BPF) testis, caput, and cauda epididymis morphometry after 28 days of exposure
From: Effect of bisphenol F, an analog of bisphenol A, on the reproductive functions of male rats
Parameter | Treatments (n = 7/group) | ||||||
|---|---|---|---|---|---|---|---|
Control | BPF 1 mg/kg | BPF 5 mg/kg | BPF 25 mg/kg | BPF 50 mg/kg | BPF 100 mg/kg | ||
Testis | Area of seminiferous tubule (%) | 90.02 ± 0.98 | 88.85 ± 2.18 | 88.87 ± 2.34 | 87.37 ± 1.34 | 86.73 ± 1.41 | 85.65 ± 2.56 |
Area of Interstitium (%) | 19.02 ± 0.79 | 18.20 ± 0.88 | 17.43 ± 0.37 | 17.27 ± 0.54 | 16.88 ± 0.41 | 15.90 ± 1.50 | |
Seminiferous tubule diameter (μm) | 213.91 ± 2.51 | 211.08 ± 5.49 | 209.09 ± 2.81 | 208.98 ± 0.72 | 207.48 ± 0.84 | 207.47 ± 1.48 | |
Epithelial height | 77.27 ± 1.94 | 74.47 ± 1.95 | 73.71 ± 3.02 | 72.38 ± 1.40 | 69.16 ± 1.30* | 68.13 ± 2.07* | |
Caput | Tubular diameter (μm) | 403.40 ± 6.76 | 399.60 ± 4.28 | 398.20 ± 3.78 | 396.20 ± 3.94 | 394.80 ± 4.61 | 396.40 ± 2.97 |
Lumen diameter (μm) | 300.00 ± 7.05 | 298.60 ± 7.50 | 295.00 ± 4.14 | 297.20 ± 4.57 | 292.60 ± 4.82 | 290.60 ± 4.34 | |
Epithelial height (μm) | 31.40 ± 1.80 | 29.40 ± 3.84 | 28.00 ± 1.41 | 28.20 ± 3.10 | 27.00 ± 0.83 | 26.60 ± 1.16 | |
Epithelium (% age) | 37.95 ± 1.99 | 34.20 ± 1.01 | 33.60 ± 0.81 | 32.80 ± 1.49 | 32.40 ± 2.59 | 32.00 ± 0.63 | |
Lumen (% age) | 70.85 ± 1.65 | 69.00 ± 3.21 | 67.86 ± 1.78 | 67.25 ± 0.91 | 68.34 ± 2.40 | 66.25 ± 7.74 | |
Cauda | Tubular diameter (μm) | 482.80 ± 4.58 | 478.60 ± 3.60 | 476.60 ± 5.26 | 477.80 ± 4.03 | 475.80 ± 6.51 | 474.80 ± 4.03 |
Lumen diameter (μm) | 432.60 ± 2.98 | 436.80 ± 4.68 | 435.20 ± 4.65 | 441.00 ± 4.32 | 438.80 ± 0.96 | 439.20 ± 3.36 | |
Epithelial height (μm) | 33.25 ± 2.32 | 34.50 ± 1.79 | 35.75 ± 0.49 | 35.80 ± 4.03 | 36.20 ± 2.07 | 38.40 ± 3.40 | |
Epithelium (% age) | 39.00 ± 1.54 | 43.75 ± 1.89 | 44.75 ± 2.10 | 42.75 ± 2.41 | 44.10 ± 1.73 | 45.00 ± 1.18 | |
Lumen (% age) | 63.25 ± 1.45 | 60.00 ± 2.87 | 62.25 ± 1.73 | 60.50 ± 2.77 | 59.25 ± 3.04 | 58.65 ± 2.47 | |