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Table 2 In vivo effect of subchronic Bisphenol F (BPF) on the different parameters

From: Effect of bisphenol F, an analog of bisphenol A, on the reproductive functions of male rats

Parameter

Treatments (n = 7/group)

Control

BPF 1 mg/kg

BPF 5 mg/kg

BPF 25 mg/kg

BPF 50 mg/kg

BPF 100 mg/kg

Body weight gain (g)

35.00 ± 4.33

26.90 ± 5.23

25.10 ± 3.21

25.00 ± 4.33

29.20 ± 5.12

27.00 ± 4.33

Right Testis weight (g)

1.04 ± 0.05

1.18 ± 0.03

1.02 ± 0.03

1.14 ± 0.06

1.22 ± 0.05

1.12 ± 0.07

Left testis weight (g)

1.16 ± 0.02

1.16 ± 0.04

1.12 ± 0.02

1.14 ± 0.05

1.16 ± 0.03

1.12 ± 0.05

SOD (u/mg protein)

45.14 ± 1.19

34.29 ± 3.75

34.38 ± 1.48

36.26 ± 5.03

31.97 ± 4.63

32.54 ± 3.38

POD (nmole)

16.55 ± 0.43

15.18 ± 0.67

13.70 ± 1.12*

12.35 ± 0.39**

13.15 ± 0.64**

13.71 ± 0.68*

CAT (u/mg Protein)

16.08 ± 0.73

14.12 ± 1.01

13.03 ± 0.57*

12.99 ± 0.70*

12.91 ± 1.01*

11.59 ± 0.59**

LPO (min/mg Tissue)

13.13 ± 0.73

12.02 ± 0.80

13.35 ± 0.32

14.93 ± 0.58

15.35 ± 0.38*

15.62 ± 0.50*

Total ROS (U/g tissue)

0.94 ± 0.20

0.89 ± 0.05

0.96 ± 0.20

2.29 ± 0.42

2.78 ± 0.47*

3.11 ± 0.61**

Protein (mg/0.5 g)

341.91 ± 6.45

287.90 ± 21.72

280.23 ± 6.62*

278.90 ± 11.16*

274.77 ± 7.90*

267.81 ± 12.44**

  1. Values are expressed as mean ± SEM. *, **, ***Significant difference at probability value P < 0.05, P < 0.01, and P < 0.001 compared to control, respectively. ANOVA followed by Dunnett’s comparison test. SOD superoxide dismutase, POD peroxidase, CAT catalase, LPO lipid peroxidation, ROS reactive oxygen species