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Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for high platelet in relation to rs3782886 genotype

From: Short stature-related single-nucleotide polymorphism (SNP) activates endothelial repair activity in elderly Japanese

 

rs3782886

P for trend

Non-minor homo

Minor homo (G/G)

Major homo (A/A)

Hetero (A/G)

No. at risk

609

332

47

 

No. of cases (percentage)

186 (30.5)

119 (35.8)

24 (51.1)

 

Model 1

1.00

1.31 (0.99, 1.74)

2.44 (1.34, 4.45)

0.002

1.00

2.21 (1.22, 3.99)

0.009

Model 2

1.00

1.49 (1.10, 2.01)

2.86 (1.52, 5.37)

< 0.001

1.00

2.40 (1.30, 4.42)

0.005

  1. Model 1 adjusted only for sex and age. Model 2 further adjusted for body mass index, systolic blood pressure, alcohol consumption (never-drinker, former drinker, current drinker [< 23 g/week, 23–45 g/week, 46–68 g/week, ≥ 69 g/week]), smoking status (never-smoker, former smoker, current smoker), HDL cholesterol, triglycerides, HbA1C, and serum creatinine. The high platelet level is defined as the highest tertiles of platelets levels (≥ 22.0 × 104/μL for men and ≥ 24.2 × 104/μL for women)