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Table 2 Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to platelet levels

From: Short stature-related single-nucleotide polymorphism (SNP) activates endothelial repair activity in elderly Japanese

 

Platelet levels

P for trend

1 SD increment of platelet

T1 (low)

T2

T3 (high)

No. at risk

332

327

329

  

No. of cases (percentage)

160 (48.2)

170 (52.0)

185 (56.2)

  

Model 1

1.00

1.22 (0.89, 1.66)

1.49 (1.09, 2.04)

0.012

1.16 (1.02, 1.33)

1.00

1.35 (1.03, 1.77)

0.029

Model 2

1.00

1.20 (0.87, 1.64)

1.47 (1.07, 2.03)

0.018

1.15 (1.01, 1.32)

1.00

1.34 (1.02, 1.77)

0.036

  1. Model 1 adjusted only for sex and age. Model 2 further adjusted for body mass index, alcohol consumption (never-drinker, former drinker, current drinker [< 23 g/week, 23–45 g/week, 46–68 g/week, ≥ 69 g/week]), smoking status (never-smoker, former smoker, current smoker), HDL cholesterol, triglycerides, HbA1C, and serum creatinine. Hypertension is defined as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Platelet levels for men are < 18.7 × 104/μL for T1, 18.7–21.9 × 104/μL for T2, and ≥ 22.0 × 104/μL for T3, for women are < 20.3 × 104/μL for T1, 20.3–24.1 × 104/μL for T2, and ≥ 24.2 × 104/μL for T3. 1 standard deviation (SD) increments of platelet are 6.23 × 104/μL for men and 5.26 × 104/μL for women