Table 4 Review for interaction of gene and alcohol intake on hypertension
Population | Gene | SNPs/gene length, bp | Chr | Position | Results | Drink | Ancestor | Reference |
|---|---|---|---|---|---|---|---|---|
Finland | APOE | Â | Â | Â | SBP | LHD | Â | 35 |
China | ADD1 | rs4961 | 4 | Â | HT | alcohol/w | Â | 37 |
China | CYP11B2 | Â | Â | Â | HT | alcohol/w | Â | 36 |
China | ALDH2 | rs2238152 | 12 | 111776655 | HT | LHD | Â | 38 |
Japan | ALDH2 | rs671 | 12 | Â | HT | alcohol/w | Â | 39 |
USA | MGC27382-PTGFR | rs648425 | 1 | 78659796 | SBP | Drinks/w | Â | 41 |
| Â | ESRRG | rs17669622 | 1 | 214823444 | MAP | Drinks/w | Â | Â |
| Â | RAB4A | rs16849553 | 1 | 227403469 | MAP | Oz alcohol/w | Â | Â |
| Â | FAM179A | rs13008299 | 2 | 29101501 | DBP | Drinks/w | Â | Â |
| Â | CRIPT-SOCS5 | rs4953404 | 2 | 46739646 | PP | Days drinks/w, Oz alcohol/w | Â | Â |
| Â | KAT2B | rs9874923 | 3 | 20076567 | MAP | Drinks/w | Â | Â |
| Â | Intergenic | rs3852160 | 5 | 5875647 | MAP | Days drinks/w | Â | Â |
| Â | ADCY2 | rs4537030 | 5 | 7296981 | MAP | Drinks/w | Â | Â |
| Â | GLI3 | rs7791745 | 7 | 42351145 | MAP | Drinks/w | Â | Â |
| Â | ZNF716 | rs11766519 | 7 | 57587798 | PP | Days drinks/w | Â | Â |
| Â | SLC16A9 | rs10826334 | 10 | 61050488 | SBP,MAP | Oz alcohol/w | Â | Â |
| Â | SLC16A9 | rs10826334 | 10 | 61050488 | SBP | Drinks/w | Â | Â |
| Â | SLIT1 | rs12773465 | 10 | 98784049 | MAP | Drinks/w | Â | Â |
| Â | SLIT1 | rs7902871 | 10 | 98799693 | DBP | Drinks/w | Â | Â |
| Â | Intergenic | rs7116456 | 11 | 23911889 | SBP | Drinks/w | Â | Â |
| Â | Intergenic | rs12292796 | 11 | 39382675 | PP | Drinks/w | Â | Â |
| Â | PDE3A | rs10841530 | 12 | 20490379 | SBP | Drinks/w | Â | Â |
| Â | KERA-LUM | rs991427 | 12 | 89998553 | SBP | Oz alcohol/w | Â | Â |
| Â | KERA-LUM | rs4494364 | 12 | 90001245 | SBP | Drinks/w | Â | Â |
| Â | RNF219-AS1 | rs9318552 | 13 | 77923788 | DBP | Oz alcohol/w | Â | Â |
| Â | CLEC3A | rs2735413 | 16 | 76611144 | SBP | Drinks/w | Â | Â |
| Â | WFDC1 | rs16963349 | 16 | 82895735 | SBP | Drinks/w | Â | Â |
| Â | FBXO15 | rs1943940 | 18 | 69856172 | DBP,MAP | Drinks/w | Â | Â |
| Â | IGSF5 | rs2410182 | 21 | 40101946 | SBP | Oz alcohol/w | Â | Â |
| Â | IGSF5-PCP4 | rs2837253 | 21 | 40143126 | SBP | Drinks/w | Â | Â |
Multiple | BLK | rs2409784 | 8 | 11539347 | DBP | CURD | EA,HA | 42 |
| Â | BLK | rs6983727 | 8 | 11558303 | SBP | LHD | EA | Â |
| Â | BLK | rs6983727 | 8 | 11558303 | PP | CURD,LHD | EA | Â |
| Â | BLK | rs34190028 | 8 | 11559641 | SBP | CURD | EA | Â |
| Â | CDH17 | rs115888294 | 8 | 94105161 | PP | CURD | AA | Â |
| Â | CORO2A | rs73655199 | 9 | 98145201 | PP | CURD | AA | Â |
| Â | ELMOD1 | rs139077481 | 11 | 107579224 | PP | CURD | AA | Â |
| Â | ERCC6 | rs4253197 | 10 | 49473111 | PP | CURD | AA | Â |
| Â | EYS | rs80158983 | 6 | 65489746 | SBP | CURD | AA | Â |
| Â | FAM167A | rs12156009 | 8 | 11427710 | SBP | CURD | EA | Â |
| Â | FAM167A | rs13255193 | 8 | 11451683 | SBP | LHD | EA | Â |
| Â | FAM167A-AS1 | rs9969423 | 8 | 11398066 | SBP | CURD,LHD | EA | Â |
| Â | FTO | rs9928094 | 16 | 53765993 | PP | CURD | ASA,EA | Â |
| Â | FTO | rs55872725 | 16 | 53775211 | SBP | CURD | EA | Â |
| Â | FTO | rs7185735 | 16 | 53788739 | PP | CURD | EA | Â |
| Â | FTO | rs62033406 | 16 | 53790314 | MAP | CURD | ASA,EA | Â |
| Â | GALNT18 | rs10741534 | 11 | 11233360 | SBP | CURD | AA | Â |
| Â | GATA4 | rs3735814 | 8 | 11749887 | SBP | CURD | EA,HA | Â |
| Â | GATA4 | rs36038176 | 8 | 11752486 | SBP | CURD | EA | Â |
| Â | LINC00208 | rs899366 | 8 | 11572976 | MAP | CURD | EA | Â |
| Â | LINC00208 | rs7464263 | 8 | 11576667 | SBP | LHD | EA | Â |
| Â | LINC00208 | rs2244894 | 8 | 11591150 | PP | CURD | ASA,EA | Â |
| Â | LINC00208 | rs1478894 | 8 | 11591245 | SBP | CURD | EA | Â |
| Â | LINC00208 | rs4841569 | 8 | 11594668 | PP | CURD,LHD | EA | Â |
| Â | LINC00208 | rs13249843 | 8 | 11601509 | DBP | CURD | EA,HA | Â |
| Â | LINC00208 | rs17807624 | 8 | 11605506 | DBP | CURD | EA | Â |
| Â | LINC00208 | rs17807624 | 8 | 11605506 | MAP | LHD | EA | Â |
| Â | LOC102723313 | rs13276026 | 8 | 10752445 | SBP | CURD | EA | Â |
| Â | LOC102723313 | rs13276026 | 8 | 10752445 | DBP,MAP | CURD | EA,HA | Â |
| Â | LOC102724880 | rs453301 | 8 | 9172877 | SBP | CURD | EA | Â |
| Â | LOC102724880 | rs453301 | 8 | 9172877 | DBP | CURD | EA,HA | Â |
| Â | LOC105372045 | rs140520944 | 18 | 29508647 | PP | CURD | AA | Â |
| Â | LOC105372361 | rs142673685 | 19 | 31669942 | PP | CURD | AA | Â |
| Â | LOC105379224 | rs2980755 | 8 | 8506173 | SBP,PP | LHD | EA | Â |
| Â | LOC105379224 | rs10092965 | 8 | 8515975 | DBP | CURD | EA,HA | Â |
| Â | LOC105379224 | rs13270194 | 8 | 8520592 | SBP | CURD | EA | Â |
| Â | LOC105379224 | rs7823056 | 8 | 8525195 | SBP,PP | LHD | AA,EA | Â |
| Â | LOC105379224 | rs6995407 | 8 | 8527137 | PP | CURD | EA | Â |
| Â | LOC105379231 | rs6601302 | 8 | 9381948 | SBP | CURD | EA | Â |
| Â | LOC105379235 | rs9650622 | 8 | 9946782 | DBP | CURD | EA | Â |
| Â | LOC105379235 | rs56243511 | 8 | 9948185 | SBP | CURD | EA | Â |
| Â | LOC105379235 | rs656319 | 8 | 9956901 | SBP,MAP | LHD | EA | Â |
| Â | LOC105379242 | rs13280442 | 8 | 11610048 | SBP,MAP | CURD,LHD | EA | Â |
| Â | LOC105379242 | rs13250871 | 8 | 11610254 | PP | CURD,LHD | EA | Â |
| Â | LOC107986913 | rs2979172 | 8 | 8452998 | PP | LHD | EA | Â |
| Â | LOC107986913 | rs2921064 | 8 | 8459127 | PP | CURD | EA | Â |
| Â | LOC107986913 | rs2979181 | 8 | 8465578 | SBP | CURD,LHD | EA | Â |
| Â | LOC157273 | rs10503387 | 8 | 9293015 | SBP | CURD | AA,EA | Â |
| Â | LOC157273 | rs11781008 | 8 | 9295729 | DBP | CURD | EA,HA | Â |
| Â | LOC157273 | rs11774915 | 8 | 9331252 | SBP | CURD | EA | Â |
|  | MIR124–1 | rs483916 | 8 | 9936091 | SBP,DBP,PP | CURD | EA |  |
|  | MIR124–1 | rs615632 | 8 | 9938811 | SBP | LHD | EA |  |
| Â | MIR4286 | rs7814795 | 8 | 10661775 | SBP | CURD,LHD | EA | Â |
| Â | MIR4286 | rs7814795 | 8 | 10661775 | MAP | CURD | EA | Â |
| Â | MIR4286 | rs28680211 | 8 | 10661935 | MAP | LHD | EA | Â |
| Â | MSRA | rs2062331 | 8 | 10122482 | DBP | CURD | EA | Â |
| Â | MSRA | rs11993089 | 8 | 10152442 | PP | CURD | EA | Â |
| Â | MSRA | rs34919878 | 8 | 10241994 | DBP | CURD | EA,HA | Â |
| Â | MSRA | rs4841294 | 8 | 10247558 | SBP | LHD | AA,EA | Â |
| Â | MSRA | rs17693945 | 8 | 10248500 | MAP | LHD | AA,EA | Â |
| Â | MSRA | rs7832708 | 8 | 10332530 | SBP | LHD | EA | Â |
| Â | MSRA | rs11786677 | 8 | 10406750 | SBP | CURD | EA | Â |
| Â | PINX1 | rs4551304 | 8 | 10807559 | DBP,MAP | CURD | EA,HA | Â |
| Â | PINX1 | rs7814757 | 8 | 10817678 | SBP | CURD | EA | Â |
| Â | RP1L1 | rs4841409 | 8 | 10658864 | SBP | CURD | EA | Â |
| Â | RP1L1 | rs4841409 | 8 | 10658864 | MAP | CURD,LHD | EA | Â |
| Â | RP1L1 | rs10096777 | 8 | 10660990 | SBP | LHD | EA | Â |
| Â | TACC2 | rs11200509 | 10 | 122256927 | PP | LHD | AA | Â |
| Â | TARID | rs76987554 | 6 | 133759717 | SBP | CURD | AA | Â |
| Â | TNKS | rs4383974 | 8 | 9761838 | SBP | CURD | AA,EA | Â |
| Â | TNKS | rs35231275 | 8 | 9762399 | PP | CURD | EA | Â |
| Â | TNKS | rs9286060 | 8 | 9795635 | DBP | CURD | AA,EA | Â |
| Â | TNKS | rs1976671 | 8 | 9822124 | SBP | CURD | EA | Â |
| Â | TNKS | rs55868514 | 8 | 9822890 | DBP | CURD | EA | Â |
| Â | UNC5D | rs79505281 | 8 | 35841899 | PP | CURD | AA | Â |
| Â | XKR6 | rs4841465 | 8 | 10962344 | SBP | CURD,LHD | EA | Â |
| Â | XKR6 | rs9969436 | 8 | 10985149 | MAP | LHD | AA,EA | Â |