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Table 2 Review for interaction of gene and salt intake on hypertension

From: Gene and environmental interactions according to the components of lifestyle modifications in hypertension guidelines

Population

Gene

SNPs/gene length, bp

Chr

Position

Trait

 

Reference

Korea

LOC101929750

rs7554672

1

219339781

HT

24hUNa, K

15

MKLN1

rs1643270

7

130826034

HT

24hUK

 

CSK

rs1378942

15

72864420

HT

24hUNa/K

 

CSK-MIR4513

rs3784789

15

72869605

HT

  

TENM4

rs10466739

11

78290369

HT

  

Taiwan

GNB3

rs5443

10

 

HT

Salt intake

22

China

CLGN

rs2567241

4

141542612

SBP, DBP, MBP

Salt intake

16

LOC105

rs11104632

12

86747816

SBP

  

UST

rs13211840

6

149153883

DBP

  

China

MKNK1

46889

1

46795665

SBP

Salt intake

17

SCOC

39097

4

141484064

SBP, DBP, MBP

  

SCOC-AS1

89668

4

141424329

DBP, MBP

  

CLGN

39210

4

141529056

SBP, DBP, MBP

  

MGAT4D

55004

4

141583978

SBP, DBP, MBP

  

LINC01478

208264

18

40157397

SBP

  

C2orf80

24704

2

208738315

PP

  

EPHA6

429464

3

98641126

PP

  

ARHGAP42

303251

11

100063616

PP

  

Japan

NPPA

rs5063

1

11907648

SBP

Salt intake

18

Japan

CYP3A5

rs776746

3

 

SBP, DBP

24hUNaCl

21

Japan

AGT

T174 M

  

HT

24hUNa, sodium intake

19

Japan

ADD1

G460 W

  

SBP

24hUNa, sodium intake

20

  1. HT hypertension, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, PP pulse pressure, 24hUNa 24-h sodium excretion; 24-h potassium excretion; 24-h salt excretion