Background factors of chemical intolerance and parent–child relationships

Table 4 Multivariable analysis for the chemical intolerance of mothers

Variables	Model 1	Model 2	Model 3
Personal factors
Eating regular meals (with)	0.50 (0.28–0.89)*		0.50 (0.28–0.91)*
Cold sensitivity (with)	2.00 (1.11–3.61)*		1.89 (1.04–3.44)*
Past medical history (mother)
Allergies
Hay fever	1.82 (1.08–3.08)*
Allergic rhinitis	1.41 (0.81–2.47)
Allergic conjunctivitis	1.18 (0.63–2.22)
Alimentary allergy	2.11 (0.74–6.01)
Atopic dermatitis	1.91 (0.99–3.67)
Any allergies^b			2.21 (1.36–3.60)**
Bronchial asthma	2.50 (1.26–4.98)**		2.84 (1.46–5.53)**
Gastric ulcer	2.06 (0.68–6.20)		1.67 (0.54–5.17)
Housing environment in elementary school-aged child
Spray of pesticide indoors (with)		1.54 (0.93–2.55)	1.27 (0.76–2.14)
Use of mosquito coil indoors (with)		1.06 (0.45–2.51)	1.10 (0.45–2.67)
Indoor pets in the first decade of life
Dog		1.30 (0.75–2.26)	1.22 (0.69–2.16)
Cat		1.99 (1.08–3.69)*	1.80 (0.95–3.41)
Psychosomatic state past month^a,b
Nervous			1.25 (1.06–1.48)**

Values are expressed as adjusted odds ratios (95% confidential interval) for 2044 participants with complete data. Significant at *p < 0.05, **p < 0.01. The predictor variables of chemical intolerance of mothers were selected from possible risk factors, possible confounders, and multicollinearity test (r < 0.5). Model 1: personal factors (eating regular meals, cold sensitivity, age, employment status, and smoking status) and past medical history; Model 2: personal factors (age, employment status, and smoking status) and housing environment when mother was an elementary school child-aged; Model 3: Model 1 (six allergic symptoms integrated into any allergic symptoms) + housing environment when mother was an elementary school child-aged and psychosomatic state (nervousness). Text in parentheses reflects case groups. ^aORs and 95% CIs for six-level linear variables were calculated using one unit of change. ^bThe six levels were (1) not at all (0%), (2) slight (20%), (3) somewhat (40%), (4) moderate (60%), (5) often (80%), and (6) always (100%)

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