The association between IGF1 gene rs1520220 polymorphism and cancer susceptibility: a meta-analysis based on 12,884 cases and 58,304 controls

Table 2 IGF1 rs1520220 polymorphism genotype distribution and allele frequency in cases and controls

	Genotype (N)								Allele frequency (N)				HWE	Score
	Case				Control				Case		Control		HWE	Score
	Total	GG	GC	CC	Total	GG	GC	CC	G	C	G	C
AI-Zahrani [18]	2036	1388	569	79	2194	1525	617	52	3345	727	3667	721	0.261	15
Chia [19]	568	378	169	21	698	452	209	37	925	211	1113	283	0.052	15
Patel [20]	6584	329	2207	4048	8424	440	2707	5277	2865	10,303	3587	13,261	< 0.001	12
Ennishi [21]	703	148	357	198	1462	361	728	373	653	753	1450	1474	0.877	12
Nakao [22]	176	33	97	46	1402	347	697	358	163	189	1391	1413	0.833	12
Qian [23]	403	71	189	143	403	78	193	132	331	475	349	457	0.620	11
Simons [24]	2274	85	691	1498	43,561	1384	12,689	29,488	861	3687	15,457	71,665	0.673	15
Li [25]	140	38	58	44	160	36	69	55	134	146	141	179	0.113	12

ISSN: 1347-4715