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Table 5 Interaction between ALDH2 rs671 polymorphism and physical activity on CAD risk

From: Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management

  ALDH2 rs671 polymorphism genotype   
  Non-risk allele carriers (G/G) Risk allele carriers (A/A + A/G) OR (95% CI) for A/A + G/G within strata of physical activity
  N cases/controls OR (95% CI) N cases/controls OR (95% CI)
Moderate/heavy
physical activity
12/59   9/49   
  1.0   0.793 (0.299–2.101)
P = 0.640
0.793 (0.299–2.101)
P = 0.640
Sedentary/light
physical activity
60/215   80/172   
  1.345 (0.669–2.701)
P = 0.406
  2.071 (1.013–4.234)
P = 0.046
1.540 (1.012–2.344)
P = 0.044
OR (95% CI) for sedentary/light physical activity within strata of genotype   1.345 (0.669–2.701)
P = 0.406
  2.612 (1.202–5.674)
P = 0.015
 
  1. Measure of interaction on additive scale: RERI (95% CI) = 0.933 (0.021 to 1.845); P value = 0.045
  2. Adjusted for age, sex, BMI, SBP, TC level, TG level, HDL-C level, current smoking, current alcohol intake, and history of diabetes mellitus
  3. Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12