Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management

Table 4 Interaction between ALDH2 rs671 polymorphism and fried food intake on CAD risk

	ALDH2 rs671 polymorphism genotype
	Non-risk allele carriers (G/G)		Risk allele carriers (A/A + A/G)
	N cases/controls	OR^† (95% CI)	N cases/controls	OR^† (95% CI)	OR^† (95% CI) for A/A + G/G within strata of fried food intake
No fried food intake	28/116		24/97
		1.0		0.954 (0.509–1.786) P = 0.882	0.954 (0.509–1.786) P = 0.882
Regular fried food intake	44/158		65/124
Regular fried food intake		1.084 (0.626–1.878) P = 0.773		1.859 (1.074–3.217) P = 0.027	1.715 (1.057–2.780) P = 0.029
OR^† (95% CI) for regular fried food intake within strata of genotype		1.084 (0.626–1.878) P = 0.773		1.949 (1.117–3.400) P = 0.019

Measure of interaction on additive scale: RERI (95% CI) = 0.821 (−0.007 to 1.649); P value = 0.052
^†Adjusted for age, sex, BMI, SBP, TC level, TG level, HDL-C level, current smoking, current alcohol intake, and history of diabetes mellitus
Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12

ISSN: 1347-4715