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Table 4 Interaction between ALDH2 rs671 polymorphism and fried food intake on CAD risk

From: Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management

  ALDH2 rs671 polymorphism genotype  
  Non-risk allele carriers (G/G) Risk allele carriers (A/A + A/G)  
  N cases/controls OR (95% CI) N cases/controls OR (95% CI) OR (95% CI) for A/A + G/G within strata of fried food intake
No fried food intake 28/116   24/97   
   1.0   0.954 (0.509–1.786)
P = 0.882
0.954 (0.509–1.786)
P = 0.882
Regular fried food intake 44/158   65/124   
  1.084 (0.626–1.878)
P = 0.773
  1.859 (1.074–3.217)
P = 0.027
1.715 (1.057–2.780)
P = 0.029
OR (95% CI) for regular fried food intake within strata of genotype   1.084 (0.626–1.878)
P = 0.773
  1.949 (1.117–3.400)
P = 0.019
 
  1. Measure of interaction on additive scale: RERI (95% CI) = 0.821 (−0.007 to 1.649); P value = 0.052
  2. Adjusted for age, sex, BMI, SBP, TC level, TG level, HDL-C level, current smoking, current alcohol intake, and history of diabetes mellitus
  3. Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12