Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management

Table 3 Interaction between ALDH2 rs671 polymorphism and dessert intake on CAD risk

	ALDH2 rs671 polymorphism genotype
	Non-risk allele carriers (G/G)		Risk allele carriers (A/A + A/G)		OR^† (95% CI) for A/A + G/G within strata of dessert intake
	N cases/controls	OR^† (95% CI)	N cases/controls	OR^† (95% CI)	OR^† (95% CI) for A/A + G/G within strata of dessert intake
No dessert intake	15/101		22/71
No dessert intake		1.0		1.950 (0.930–4.088) P = 0.077	1.950 (0.930–4.088) P = 0.077
Regular dessert intake	57/173		67/150
Regular dessert intake	57/173	2.095 (1.113–3.944) P = 0.022		2.539 (1.335–4.829) P = 0.004	1.212 (0.773–1.901) P = 0.402
OR^† (95% CI) for regular dessert intake within strata of genotype		2.095 (1.113–3.944) P = 0.022		1.302 (0.727–2.331) P = 0.374

Measure of interaction on additive scale: RERI (95% CI) = − 0.506 (− 2.110 to 1.099); P value = 0.537
^†Adjusted for age, sex, BMI, SBP, TC level, TG level, HDL-C level, current smoking, current alcohol intake, and history of diabetes mellitus
Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12

ISSN: 1347-4715