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Table 2 Associations of ALDH2 rs671 polymorphism with CAD risk in three genetic models

From: Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management

ALDH2 rs671 CAD cases
n (%)
Control subjects
n (%)
Crude OR
(95% CI)
P value Adjusted OR
(95% CI)
P value
Additive model
 G 215 742 1.0   1.0  
 A 107 248 1.508 (1.141–1.994) 0.004 1.483 (1.114–1.974) 0.007
Dominant model
 G/G 72 274 1.0   1.0  
 A/G + A/A 89 221 1.533 (1.072–2.192) 0.019 1.492 (1.036–2.148) 0.032
Recessive model
 A/G + G/G 143 468 1.0   1.0  
 A/A 18 27 2.182 (1.168–4.077) 0.014 2.161 (1.139–4.101) 0.018
  1. Adjusted for age, gender, BMI, TG level, TC level, HDL-C level, SBP, current smoking status, current alcohol intake status, and the history of diabetes mellitus
  2. Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12