Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management

Table 2 Associations of ALDH2 rs671 polymorphism with CAD risk in three genetic models

ALDH2 rs671	CAD cases n (%)	Control subjects n (%)	Crude OR (95% CI)	P value	Adjusted OR^† (95% CI)	P value
Additive model
G	215	742	1.0		1.0
A	107	248	1.508 (1.141–1.994)	0.004	1.483 (1.114–1.974)	0.007
Dominant model
G/G	72	274	1.0		1.0
A/G + A/A	89	221	1.533 (1.072–2.192)	0.019	1.492 (1.036–2.148)	0.032
Recessive model
A/G + G/G	143	468	1.0		1.0
A/A	18	27	2.182 (1.168–4.077)	0.014	2.161 (1.139–4.101)	0.018

^†Adjusted for age, gender, BMI, TG level, TC level, HDL-C level, SBP, current smoking status, current alcohol intake status, and the history of diabetes mellitus
Italic values are statistically significant with P value < 0.05 and maintains significance using the Benjamini–Hochberg procedure with the false discovery rate at 0.12

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