Fig. 3
From: The effect of noise exposure on insulin sensitivity in mice may be mediated by the JNK/IRS1 pathway
Effect of noise exposure on insulin signaling pathways in the gastrocnemius muscle. a Levels of total and Thr183/Tyr185 phosphorylated JNK, total and Ser307 phosphorylated IRS1, and total Akt and phosphorylated Akt at Ser473 and Thr308 were detected via immunoblotting, and representative Western blots are presented. b–e Graphs showing the relative intensities of phospho-protein bands are normalized to the corresponding total protein levels in each case. The data are expressed relative to values for age-matched controls. The average of each age-matched control group was set to 1. Values are presented as the mean ± SEM of 8 mice per group. *p < 0.05 and **p < 0.01 indicate significantly different mean values in the post hoc comparisons between N20D and the control after a one-way ANOVA, demonstrating a significant effect of noise. #p < 0.05 indicates N10D vs control group. $p < 0.05 indicates N1D vs control