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Table 2 Linear regression analysis of the association between selected variables and max IMT

From: Oxidized human serum albumin as a possible correlation factor for atherosclerosis in a rural Japanese population: the results of the Yakumo Study

Independent variables

Unadjusted model

Age- and sex-adjusted model

Fully adjusted model

βS (βU)

[95% CI]

p value

βS (βU)

[95% CIc]

p value

βS (βU)

[95% CIc]

p value

f(HMA)a

− 0.25 (− 0.018)

[− 0.027, − 0.010]

< 0.01

− 0.10 (− 0.007)

[− 0.016, 0.001]

0.09

− 0.13 (− 0.010)

[− 0.018, − 0.001]

0.03

Sex (male)

− 0.28 (− 0.277)

[− 0.388, − 0.165]

< 0.01

− 0.24 (− 0.230)

[− 0.340, − 0.130]

< 0.01

− 0.15 (− 0.151)

[− 0.294, − 0.009]

0.04

Age

0.42 (0.023)

[0.017, 0.028]

< 0.01

0.35 (0.019)

[0.012, 0.025]

< 0.01

0.32 (0.017)

[0.010, 0.025]

< 0.01

Body mass index

− 0.01 (− 0.002)

[− 0.018, 0.014]

0.84

  

− 0.12 (− 0.016)

[− 0.031, − 0.001]

0.04

Mean blood pressureb

0.26 (0.009)

[0.005, 0.014]

< 0.01

  

0.13 (0.005)

[0.000, 0.009]

0.03

Blood glucose

0.16 (0.005)

[0.001, 0.009]

0.01

  

0.07 (0.002)

[− 0.002, 0.006]

0.27

Triacylglycerides

0.01 (0.000)

[− 0.001, 0.001]

0.82

  

− 0.02 (0.000)

[− 0.001, 0.001]

0.68

HDL cholesterol

− 0.14 (− 0.005)

[− 0.008, − 0.001]

0.02

  

− 0.02 (− 0.001)

[− 0.005, 0.004]

0.80

LDL cholesterol

0.02 (0.000)

[− 0.001, 0.002]

0.72

  

0.11 (0.002)

[0.000, 0.003]

0.04

Smoking status

Ever

0.09 (0.097)

[− 0.029, 0.223]

0.13

  

0.07 (0.075)

[− 0.062, 0.211]

0.28

Current

0.00 (− 0.006)

[− 0.189, 0.177]

0.95

  

0.05 (0.074)

[− 0.105, 0.253]

0.42

Alcohol consumption

Ever

0.14 (0.329)

[0.054, 0.605]

0.02

  

0.10 (0.235)

[− 0.020, 0.490]

0.07

Current

0.11 (0.112)

[− 0.007, 0.232]

0.07

  

0.03 (0.026)

[− 0.100, 0.152]

0.69

Exercise habits

1–2 h/week

0.09 (0.098)

[− 0.042, 0.239]

0.17

  

0.07 (0.082)

[− 0.047, 0.211]

0.21

3–4 h/week

0.07 (0.107)

[− 0.080, 0.294]

0.26

  

0.05 (0.072)

[− 0.096, 0.240]

0.40

≥ 5 h/week

0.16 (0.238)

[0.058, 0.419]

0.01

  

0.08 (0.118)

[− 0.051, 0.287]

0.17

Medication for non-communicable diseases (present)

0.17 (0.176)

[0.058, 0.295]

< 0.01

  

0.04 (0.043)

[− 0.080, 0.165]

0.49

  1. IMT denotes intima-media thickness, βS denotes standardized β, βU denotes unstandardized β, and CI denotes confidence interval
  2. aFraction of human mercaptalbumin
  3. bCalculated as (2 × diastolic pressure + systolic pressure)/3