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Table 1 Characteristics of cases and controls

From: Association between NAT2, CYP1A1, and CYP1A2 genotypes, heterocyclic aromatic amines, and prostate cancer risk: a case control study in Japan

Characteristics

Cases

Controls

P

Number

351

351

 

Age, years; mean (SD)

64.9 (0.35)

64.9 (0.35)

1.00b

 < 65; n (%)

180 (51.3%)

180 (51.3%)

 

 ≥ 65; n (%)

171 (48.7%)

171 (48.7%)

1.00a

Family history of prostate cancer; n (%)

13 (3.7%)

4 (1.1%)

0.027a

Alcohol consumption, g/week; mean (SD)

151.6 (192.4)

196.0 (207.2)

< 0.001b

Smoking status; n (%)

 Never

126 (35.9%)

108 (30.8%)

 

 Ever

225 (64.1%)

243 (69.2%)

0.15a

 Current smoker

55 (15.7%)

67 (19.1%)

0.23a

 Ex-smoker

170 (48.4%)

176 (50.1%)

0.65a

BMI, kg/m2; mean (SD)

23.8 (0.14)

23.8 (0.13)

1.00b

Total HAA intake, ng/day; mean (SD)

46.5 (1.6)

38.2 (1.7)

< 0.001b

 Trp-P-1 intake

3.9 (0.23)

3.1 (0.19)

< 0.001b

 IQ intake

0.32 (0.021)

0.27 (0.018)

0.012b

 MeIQ intake

5.9 (0.21)

4.8 (0.17)

< 0.001b

 MeIQx intake

6.4 (0.21)

5.2 (0.20)

< 0.001b

 4,8-DiMelQx intake

0.41 (0.34)

0.36 (0.33)

0.10b

 7,8-DiMelQx intake

1.6 (0.14)

1.4 (0.14)

0.06b

 PhIP intake

28.2 (0.98)

23.3 (0.93)

< 0.001 b

Total energy intake, kcal/day; mean (SD)

1869.2 (567.8)

1789.3 (519.9)

0.30b

Meat intake, g/day; mean (SD)

59.9 (41.0)

50.2 (36.1)

0.84b

Red meat intake, g/day; mean (SD)

47.3 (33.8)

37.6 (31.0)

0.87b

Processed meat intake, g/day; mean (SD)

7.1 (7.9)

6.3 (8.6)

0.42b

Fish intake, g/day; mean (SD)

84.2 (58.3)

77.4 (62.8)

0.51b

Vegetable intake, g/day; mean (SD)

88.7 (68.4)

82.7 (73.2)

0.24b

NaCl intake, g/day; mean (SD)

10.1 (4.5)

9.2 (4.1)

0.79b

Participants with preference on meat cooked level as well done or very well done (%)

33 (50.7%)

26(44%)

0.40a

Participants with preference on eating almost all of grilled fish skin (%)

71 (50.4%)

70 (49.6%)

0.99a

  1. BMI body mass index; SD standard deviation; HAA heterocyclic aromatic amine; NaCl sodium chloride; Trp-P-1 3-Amino-1, 4-dimethyl-5H-pyrido[4, 3-b]indole; IQ 2-Amino-3-methylimidazo[4,5-f]quinoline; MeIQ 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline; MeIQx 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline; 4,8-DiMelQx 2-Amino-3, 4, 8-trimethylimidazo[4, 5-f]quinoxaline; 7,8-DiMelQx 2-Amino-3, 7, 8-trimethylimidazo[4, 5-f]quinoxaline; PhIP 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
  2. aChi-square test
  3. bMann-Whitney test