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Table 4 Effect of C. nudiflora on CCl4-induced changes in phase II metabolizing enzymes

From: The potential protective effect of Commelina nudiflora L. against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats, mediated by suppression of oxidative stress and inflammation

Groups

Glutathione S-transferase activity (nmol CDNB conjugate formed/min/mg protein)

Quinone reductase activity (nmol 2,6-DCIP reduced/min/mg protein)

Saline control

253.55 ± 11.49

313.17 ± 27.7

CCl4 (1 ml/kg b.wt.)

118.44 ± 7.53#

161.99 ± 6.9#

C. nudiflora (150 mg/kg b.wt.) + CCl4

148.19 ± 2.63*

220.99 ± 15.4*

C. nudiflora (300 mg/kg b.wt.) + CCl4

174.76 ± 9.49*

240.62 ± 12.53*

C. nudiflora (450 mg/kg b.wt.) + CCl4

210.34 ± 16.06*

260.15 ± 6.14*

C. nudiflora (450 mg/kg b.wt.)

254.26 ± 9.90*

312.51 ± 11.97*

  1. Each value represents the mean ± S.E. of six animals
  2. #Significant at p < 0.05 compared to the control group; *significant at p < 0.05 compared to the CCl4-treated group
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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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