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Table 3 Effect of C. nudiflora on CCl4-induced changes in antioxidant enzymes

From: The potential protective effect of Commelina nudiflora L. against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats, mediated by suppression of oxidative stress and inflammation

Groups

Glutathione peroxidase (nmol NADPH oxidized/min/mg protein)

Glutathione reductase (nmol NADPH oxidized/min/mg protein)

Catalase (nmol H2O2 consumed/min/mg protein)

Glucose-6-phosphate dehydrogenase (nmol NADPH formed/min/mg protein)

Saline control

61.87 ± 1.93

50.61 ± 1.32

0.82 ± 0.01

40.05 ± 1.37

CCl4 (1 ml/kg b.wt.)

47.89 ± 2.06#

38.62 ± 1.05#

0.50 ± 0.12#

21.14 ± 1.67#

C. nudiflora (150 mg/kg b.wt.) + CCl4

55.18 ± 3.95*

45.64 ± 3.66*

0.68 ± 0.05*

33.35 ± 1.53*

C. nudiflora (300 mg/kg b.wt.) + CCl4

59.18 ± 2.08*

46.61 ± 1.03*

0.70 ± 0.04*

34.33 ± 1.41*

C. nudiflora (450 mg/kg b.wt.) + CCl4

61.17 ± 4.74*

47.56 ± 0.71*

0.74 ± 0.02*

35.80 ± 0.9*

C. nudiflora (450 mg/kg b.wt.)

61.99 ± 5.15*

50.11 ± 1.59*

0.81 ± 0.04*

40.15 ± 1.35*

  1. Each value represents the mean ± S.E. of six animals
  2. #Significant at p < 0.05 compared to the control group; *significant at p < 0.05 compared to the CCl4-treated group
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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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