Impact of single nucleotide polymorphism on short stature and reduced tongue pressure among community-dwelling elderly Japanese participants: a cross-sectional study

Table 5 Odds ratios (OR) and 95% confidence intervals (CI) for short stature and reduced maximum voluntary tongue pressure against the palate (MTP) in relation to the rs3782886 genotype among participants with BMI < 25 kg/m²

	rs3782886			p for trend	Minor allele frequencies
	Non-minor homo		Minor homo
	Major homo (A/A)	Hetero (A/G)	(G/G)
Short stature
Total participants (BMI < 25 kg/m²)
No. at risk	232	123	17
No. of cases (percentage)	56 (24.1)	30 (24.4)	9 (52.9)
Model 1	1.00	0.96 (0.55, 1.68)	4.18 (1.37, 12.75)	0.127	1.39 (0.91, 2.13)
Model 1	1.00		4.23 (1.41, 12.72)	0.010
Model 2	1.00	1.03 (0.57, 1.86)	4.25 (1.35, 13.39)	0.092	1.47 (0.94, 2.31)
Model 2	1.00		4.21 (1.36, 12.98)	0.012
Reduced maximum voluntary tongue pressure against the palate (MTP)
Total participants (BMI < 25 kg/m²)
No. at risk	232	123	17
No. of cases (percentage)	82 (35.3)	44 (35.8)	11 (64.7)
Model 1	1.00	1.00 (0.62, 1.61)	3.56 (1.21, 10.53)	0.149	1.32 (0.91, 1.92)
Model 1	1.00		3.57 (1.22, 10.43)	0.020
Model 2	1.00	1.11 (0.66, 1.86)	4.49 (1.45, 13.92)	0.054	1.49 (0.99, 2.24)
Model 2	1.00		4.31 (1.41, 13.11)	0.010

Model 1: adjusted only for sex and age. Model 2: further adjusted for body mass index, systolic blood pressure, alcohol consumption (never drinker, former drinker, current drinker [<23, 23–45, 46–68, and ≥69 g/week]), smoking status (never smoker, former smoker, current smoker), history of stroke, HDL-cholesterol, triglycerides, HbA1C, and serum creatinine. Short stature is defined as a height level at or under the 25th percentile of the study population (<158.0cm for men and <145.0 cm for women). Reduced maximum voluntary tongue pressure against the palate is defined as the lowest tertile of the study population (<26.5 kPa for men and <24.1 kPa for women)

ISSN: 1347-4715