Skip to main content

Table 5 The odds ratios for evaluating metabolic syndrome, DM, dyslipidemia, or hypertension adjusting for additional factors

From: Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population

  aMetabolic syndrome bDM cDyslipidemia dHypertension
  Odds ratio p-value Odds ratio p-value Odds ratio p-value Odds ratio p-value
Val 1.48 (1.33–1.64) <0.001 1.67 (1.50–1.87) <0.001 1.48 (1.39–1.58) <0.001 1.01 (0.94–1.08) 0.816
Leu 1.39 (1.25–1.54) <0.001 1.59 (1.41–1.78) <0.001 1.57 (1.47–1.68) <0.001 0.95 (0.88–1.02) 0.137
Ile 1.46 (1.32–1.62) <0.001 1.52 (1.36–1.69) <0.001 1.43 (1.34–1.53) <0.001 1.03 (0.96–1.11) 0.414
Trp 1.07 (0.97–1.18) 0.169 0.88 (0.79–0.98) 0.024 1.25 (1.18–1.32) <0.001 0.98 (0.92–1.04) 0.471
Phe 0.96 (0.87–1.07) 0.470 1.10 (1.00–1.21) 0.051 1.01 (0.95–1.07) 0.794 0.98 (0.92–1.04) 0.503
Tyr 1.08 (0.98–1.19) 0.115 1.07 (0.97–1.18) 0.164 0.96 (0.91–1.02) 0.151 1.01 (0.95–1.08) 0.740
Ala 1.70 (1.55–1.87) <0.001 1.47 (1.33–1.63) <0.001 1.34 (1.26–1.42) <0.001 1.08 (1.01–1.15) 0.021
Gly 0.76 (0.67–0.86) <0.001 0.76 (0.67–0.86) <0.001 0.96 (0.91–1.01) 0.079 0.93 (0.88–0.99) 0.020
Gln 0.77 (0.70–0.84) <0.001 0.93 (0.84–1.03) 0.161 1.01 (0.96–1.06) 0.688 0.89 (0.84–0.94) <0.001
Ser 0.82 (0.74–0.91) <0.001 1.27 (1.14–1.40) <0.001 0.88 (0.84–0.93) <0.001 0.87 (0.82–0.93) <0.001
His 1.05 (0.98–1.13) 0.137 1.03 (0.95–1.12) 0.432 1.05 (0.99–1.11) 0.109 0.89 (0.81–0.97) 0.007
Lys 1.14 (1.04–1.26) 0.005 1.24 (1.12–1.36) <0.001 1.25 (1.18–1.32) <0.001 0.91 (0.86–0.97) 0.002
Met 1.04 (0.97–1.11) 0.328 1.09 (1.02–1.17) 0.017 0.98 (0.93–1.04) 0.593 0.95 (0.89–1.02) 0.127
Thr 1.17 (1.08–1.27) <0.001 1.05 (0.95–1.15) 0.350 0.98 (0.93–1.03) 0.421 1.06 (1.00–1.12) 0.061
Asn 0.84 (0.76–0.92) <0.001 1.08 (0.98–1.19) 0.103 0.90 (0.85–0.95) <0.001 0.92 (0.87–0.98) 0.008
Cit 0.98 (0.88–1.08) 0.648 1.13 (1.03–1.24) 0.011 1.02 (0.97–1.08) 0.463 1.04 (0.98–1.10) 0.253
Arg 1.01 (0.92–1.11) 0.824 1.15 (1.05–1.27) 0.003 1.11 (1.05–1.16) <0.001 0.99 (0.93–1.05) 0.658
Pro 1.38 (1.27–1.50) <0.001 1.25 (1.15–1.36) <0.001 1.20 (1.14–1.27) <0.001 1.05 (0.99–1.12) 0.137
Orn 1.06 (0.97–1.17) 0.217 1.18 (1.09–1.29) <0.001 1.11 (1.05–1.18) <0.001 0.99 (0.93–1.05) 0.716
Index 1 1.88 (1.68–2.11) <0.001 1.83 (1.62–2.06) <0.001 1.36 (1.28–1.45) <0.001 1.12 (1.04–1.20) 0.003
Index 2 1.44 (1.29–1.60) <0.001 1.37 (1.22–1.53) <0.001 1.24 (1.16–1.33) <0.001 1.12 (1.04–1.21) 0.002
  1. Values are odds ratios (95% confidence intervals) as a continuous variable per SD increment for developing metabolic syndrome, DM, dyslipidemia, or hypertension from logistic regressions
  2. aAdjusted for age, gender and BMI
  3. bAdjusted for age, gender, BMI, LDL-C, HDL-C, TG, SBP and DBP
  4. cAdjusted for age, gender, BMI, FPG, HbA1c, SBP and DBP
  5. dAdjusted for age, gender, BMI, FPG, HbA1c, LDL-C, HDL-C and TG