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Table 5 The odds ratios for evaluating metabolic syndrome, DM, dyslipidemia, or hypertension adjusting for additional factors

From: Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population

 

aMetabolic syndrome

bDM

cDyslipidemia

dHypertension

 

Odds ratio

p-value

Odds ratio

p-value

Odds ratio

p-value

Odds ratio

p-value

Val

1.48

(1.33–1.64)

<0.001

1.67

(1.50–1.87)

<0.001

1.48

(1.39–1.58)

<0.001

1.01

(0.94–1.08)

0.816

Leu

1.39

(1.25–1.54)

<0.001

1.59

(1.41–1.78)

<0.001

1.57

(1.47–1.68)

<0.001

0.95

(0.88–1.02)

0.137

Ile

1.46

(1.32–1.62)

<0.001

1.52

(1.36–1.69)

<0.001

1.43

(1.34–1.53)

<0.001

1.03

(0.96–1.11)

0.414

Trp

1.07

(0.97–1.18)

0.169

0.88

(0.79–0.98)

0.024

1.25

(1.18–1.32)

<0.001

0.98

(0.92–1.04)

0.471

Phe

0.96

(0.87–1.07)

0.470

1.10

(1.00–1.21)

0.051

1.01

(0.95–1.07)

0.794

0.98

(0.92–1.04)

0.503

Tyr

1.08

(0.98–1.19)

0.115

1.07

(0.97–1.18)

0.164

0.96

(0.91–1.02)

0.151

1.01

(0.95–1.08)

0.740

Ala

1.70

(1.55–1.87)

<0.001

1.47

(1.33–1.63)

<0.001

1.34

(1.26–1.42)

<0.001

1.08

(1.01–1.15)

0.021

Gly

0.76

(0.67–0.86)

<0.001

0.76

(0.67–0.86)

<0.001

0.96

(0.91–1.01)

0.079

0.93

(0.88–0.99)

0.020

Gln

0.77

(0.70–0.84)

<0.001

0.93

(0.84–1.03)

0.161

1.01

(0.96–1.06)

0.688

0.89

(0.84–0.94)

<0.001

Ser

0.82

(0.74–0.91)

<0.001

1.27

(1.14–1.40)

<0.001

0.88

(0.84–0.93)

<0.001

0.87

(0.82–0.93)

<0.001

His

1.05

(0.98–1.13)

0.137

1.03

(0.95–1.12)

0.432

1.05

(0.99–1.11)

0.109

0.89

(0.81–0.97)

0.007

Lys

1.14

(1.04–1.26)

0.005

1.24

(1.12–1.36)

<0.001

1.25

(1.18–1.32)

<0.001

0.91

(0.86–0.97)

0.002

Met

1.04

(0.97–1.11)

0.328

1.09

(1.02–1.17)

0.017

0.98

(0.93–1.04)

0.593

0.95

(0.89–1.02)

0.127

Thr

1.17

(1.08–1.27)

<0.001

1.05

(0.95–1.15)

0.350

0.98

(0.93–1.03)

0.421

1.06

(1.00–1.12)

0.061

Asn

0.84

(0.76–0.92)

<0.001

1.08

(0.98–1.19)

0.103

0.90

(0.85–0.95)

<0.001

0.92

(0.87–0.98)

0.008

Cit

0.98

(0.88–1.08)

0.648

1.13

(1.03–1.24)

0.011

1.02

(0.97–1.08)

0.463

1.04

(0.98–1.10)

0.253

Arg

1.01

(0.92–1.11)

0.824

1.15

(1.05–1.27)

0.003

1.11

(1.05–1.16)

<0.001

0.99

(0.93–1.05)

0.658

Pro

1.38

(1.27–1.50)

<0.001

1.25

(1.15–1.36)

<0.001

1.20

(1.14–1.27)

<0.001

1.05

(0.99–1.12)

0.137

Orn

1.06

(0.97–1.17)

0.217

1.18

(1.09–1.29)

<0.001

1.11

(1.05–1.18)

<0.001

0.99

(0.93–1.05)

0.716

Index 1

1.88

(1.68–2.11)

<0.001

1.83

(1.62–2.06)

<0.001

1.36

(1.28–1.45)

<0.001

1.12

(1.04–1.20)

0.003

Index 2

1.44

(1.29–1.60)

<0.001

1.37

(1.22–1.53)

<0.001

1.24

(1.16–1.33)

<0.001

1.12

(1.04–1.21)

0.002

  1. Values are odds ratios (95% confidence intervals) as a continuous variable per SD increment for developing metabolic syndrome, DM, dyslipidemia, or hypertension from logistic regressions
  2. aAdjusted for age, gender and BMI
  3. bAdjusted for age, gender, BMI, LDL-C, HDL-C, TG, SBP and DBP
  4. cAdjusted for age, gender, BMI, FPG, HbA1c, SBP and DBP
  5. dAdjusted for age, gender, BMI, FPG, HbA1c, LDL-C, HDL-C and TG
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