Skip to main content

Table 4 The odds ratios for evaluating metabolic syndrome, DM, dyslipidemia, or hypertension adjusting for age and gender

From: Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population

  Metabolic syndrome DM Dyslipidemia Hypertension
  Odds ratio p-value Odds ratio p-value Odds ratio p-value Odds ratio p-value
Val 2.16 (1.98–2.36) <0.001 1.91 (1.73–2.11) <0.001 1.79 (1.69–1.89) <0.001 1.30 (1.23–1.37) <0.001
Leu 2.04 (1.86–2.23) <0.001 1.82 (1.63–2.02) <0.001 1.88 (1.77–2.00) <0.001 1.23 (1.15–1.30) <0.001
Ile 1.97 (1.80–2.15) <0.001 1.75 (1.58–1.93) <0.001 1.69 (1.59–1.79) <0.001 1.27 (1.20–1.35) <0.001
Trp 1.27 (1.17–1.37) <0.001 0.99 (0.89–1.10) 0.859 1.36 (1.29–1.43) <0.001 1.11 (1.05–1.17) <0.001
Phe 1.34 (1.24–1.45) <0.001 1.20 (1.10–1.31) <0.001 1.15 (1.10–1.21) <0.001 1.13 (1.07–1.20) <0.001
Tyr 1.65 (1.52–1.78) <0.001 1.24 (1.13–1.36) <0.001 1.16 (1.10–1.22) <0.001 1.25 (1.19–1.32) <0.001
Ala 2.15 (1.98–2.33) <0.001 1.70 (1.55–1.86) <0.001 1.53 (1.45–1.61) <0.001 1.37 (1.30–1.45) <0.001
Gly 0.57 (0.51–0.64) <0.001 0.69 (0.61–0.78) <0.001 0.87 (0.83–0.91) <0.001 0.84 (0.80–0.89) <0.001
Gln 0.83 (0.77–0.90) <0.001 0.92 (0.83–1.01) 0.082 1.01 (0.97–1.06) 0.581 0.85 (0.80–0.89) <0.001
Ser 0.76 (0.70–0.83) <0.001 1.14 (1.04–1.26) 0.008 0.83 (0.79–0.87) <0.001 0.80 (0.76–0.85) <0.001
His 1.06 (1.01–1.13) 0.031 1.05 (0.99–1.11) 0.134 1.17 (1.09–1.25) <0.001 0.99 (0.94–1.05) 0.739
Lys 1.35 (1.25–1.47) <0.001 1.30 (1.19–1.43) <0.001 1.39 (1.32–1.47) <0.001 1.02 (0.97–1.08) 0.398
Met 1.16 (1.07–1.26) <0.001 1.13 (1.05–1.21) 0.002 1.06 (1.00–1.11) 0.038 1.03 (0.97–1.08) 0.326
Thr 1.18 (1.10–1.28) <0.001 1.10 (1.00–1.21) 0.042 1.02 (0.97–1.07) 0.404 1.12 (1.07–1.18) <0.001
Asn 0.79 (0.72–0.86) <0.001 1.05 (0.95–1.15) 0.321 0.87 (0.83–0.91) <0.001 0.89 (0.84–0.93) <0.001
Cit 0.84 (0.77–0.93) <0.001 1.10 (1.00–1.20) 0.053 0.97 (0.92–1.01) 0.160 0.93 (0.88–0.99) 0.013
Arg 1.00 (0.92–1.08) 0.993 1.13 (1.03–1.24) 0.009 1.12 (1.07–1.17) <0.001 0.98 (0.93–1.03) 0.482
Pro 1.46 (1.36–1.57) <0.001 1.34 (1.24–1.46) <0.001 1.31 (1.25–1.38) <0.001 1.17 (1.11–1.24) <0.001
Orn 1.16 (1.07–1.26) <0.001 1.23 (1.14–1.33) <0.001 1.16 (1.11–1.22) <0.001 1.04 (0.98–1.09) 0.205
Index 1 3.23 (2.92–3.57) <0.001 2.10 (1.89–2.33) <0.001 1.69 (1.61–1.79) <0.001 1.52 (1.44–1.61) <0.001
Index 2 2.37 (2.16–2.61) <0.001 1.66 (1.50–1.84) <0.001 1.53 (1.45–1.62) <0.001 1.48 (1.39–1.57) <0.001
  1. Values are odds ratios (95% confidence intervals) as a continuous variable per SD increment for developing metabolic syndrome, DM, dyslipidemia, or hypertension from logistic regressions