Variables | Maternal blood | Cord blood | |||||||
---|---|---|---|---|---|---|---|---|---|
n | DHA | EPA | ARA | n | DHA | EPA | ARA | ||
Maternal education | |||||||||
< 13 | 819 | 7.3 (3.2–11.0) | 0.67 (0.11–2.96) | 11.7 (7.3–14.5) | 770 | 6.8 (3.3–10.5) | 0.28 (0.02–2.54) | 15.5 (9.0–19.9) | |
≥ 13 | 707 | 7.6 (4.1–10.7) | 0.80 (0.16–4.10) | 11.5 (6.6–16.2) | 660 | 6.9 (3.1–10.7) | 0.31 (0.03–2.30) | 15.4 (9.7–20.0) | |
p | <.0001 | <.0001 | 0.060 | 0.13 | <.0001 | 0.11 | |||
Household income (million Japanese Yen) | |||||||||
< 2 | 105 | 7.3 (4.3–10.3) | 0.68 (0.25–2.05) | 11.6 (8.1–14.0) | 97 | 6.8 (3.9–9.5) | 0.29 (0.08–2.30) | 15.5 (9.0–19.9) | |
2 to <4 | 592 | 7.3 (3.2–11.0) | 0.68 (0.14–3.00) | 11.7 (7.3–14.6) | 556 | 6.8 (3.1–10.5) | 0.27 (0.03–2.54) | 15.5 (10.9–20.0) | |
4 to <6 | 395 | 7.4 (3.9–10.5) | 0.74 (0.11–2.40) | 11.6 (6.9–14.1) | 364 | 6.8 (3.4–10.7) | 0.30 (0.02–2.04) | 15.5 (9.7–18.4) | |
6 to <8 | 171 | 7.7 (4.4–10.7) | 0.80 (0.29–4.10) | 11.5 (8.3–16.2) | 160 | 7.0 (3.9–9.8) | 0.33 (0.07–1.71) | 15.4 (10.9–18.7) | |
≥ 8 | 133 | 7.7 (4.8–10.1) | 0.87 (0.31–3.44) | 11.4 (7.1–14.5) | 126 | 6.9 (3.3–9.1) | 0.31 (0.08–1.38) | 15.3 (10.7–19.6) | |
p | 0.0005 | <.0001 | 0.14 | 0.67 | 0.0004 | 0.33 | |||
Living together with parents | |||||||||
Yes | 661 | 7.5 (3.2–11.0) | 0.75 (0.16–3.44) | 11.6 (7.1–14.3) | 629 | 6.8 (3.3–10.7) | 0.29 (0.03–2.54) | 15.4 (9.7–20.0) | |
No | 883 | 7.4 (3.9–10.9) | 0.70 (0.11–4.10) | 11.6 (6.6–16.2) | 811 | 6.8 (3.1–10.5) | 0.29 (0.02–2.30) | 15.5 (9.0–19.9) | |
p | 0.11 | 0.081 | 0.28 | 0.81 | 0.082 | 0.074 | |||
Smoking habits | |||||||||
Never smoked | 698 | 7.5 (3.9–11.0) | 0.75 (0.24–4.10) | 11.6 (6.6–16.2) | 654 | 6.8 (3.1–10.5) | 0.29 (0.05–2.54) | 15.4 (9.0–19.6) | |
Ex-smokers who quit before pregnancy | 378 | 7.5 (4.3–10.3) | 0.75 (0.11–2.88) | 11.5 (7.2–14.3) | 355 | 6.9 (3.3–9.4) | 0.30 (0.02–1.60) | 15.4 (9.7–18.6) | |
Ex-smokers who quit after pregnancy | 330 | 7.2 (3.2–10.8) | 0.67 (0.14–2.16) | 11.6 (7.3–14.5) | 303 | 6.8 (3.4–10.7) | 0.26 (0.03–1.69) | 15.5 (9.7–20.0) | |
Smokers during early pregnancy | 137 | 7.1 (4.4–10.5) | 0.68 (0.21–3.00) | 11.7 (6.9–14.0) | 126 | 6.8 (4.4–10.5) | 0.27 (0.07–0.87) | 15.5 (11.6–19.9) | |
p | <.0001 | 0.0010 | 0.16 | 0.75 | 0.0045 | 0.38 | |||
Passive smoking | |||||||||
Yes | 1075 | 7.3 (3.2–10.9) | 0.70 (0.11–4.10) | 11.6 (6.6–16.2) | 1008 | 6.8 (3.1–10.5) | 0.28 (0.02–2.54) | 15.5 (9.0–20.0) | |
No | 470 | 7.6 (3.9–11.0) | 0.79 (0.25–2.68) | 11.6 (7.2–14.6) | 432 | 6.8 (3.3–10.7) | 0.31 (0.05–1.38) | 15.4 (10.2–18.6) | |
p | <.0001 | <.0001 | 0.19 | 0.45 | 0.0014 | 0.11 | |||
Alcohol consumption | |||||||||
Yes | 29 | 7.6 (4.3–9.3) | 0.75 (0.42–1.69) | 11.2 (9.6–13.1) | 26 | 7.0 (4.0–8.6) | 0.27 (0.13–0.64) | 15.3 (10.2–18.1) | |
No | 1498 | 7.4 (3.2–11.0) | 0.73 (0.11–4.10) | 11.6 (6.6–16.2) | 1405 | 6.8 (3.1–10.7) | 0.29 (0.02–2.54) | 15.5 (9.0–20.0) | |
p | 0.78 | 0.50 | 0.12 | 0.91 | 0.87 | 0.72 | |||
Parity | |||||||||
Primipara | 574 | 7.4 (3.2–11.0) | 0.72 (0.16–4.10) | 11.6 (6.6–14.1) | 525 | 6.8 (3.1–10.7) | 0.30 (0.03–2.30) | 15.4 (9.7–20.0) | |
Multipara | 947 | 8.2 (3.9–10.7) | 0.73 (0.11–3.44) | 11.6 (6.9–16.2) | 893 | 6.8 (3.3–10.5) | 0.29 (0.02–2.54) | 15.5 (9.0–19.9) | |
p | 0.62 | 0.88 | 0.87 | 0.13 | 0.23 | 0.037 | |||
Supplemental use | |||||||||
Any kind | Yes | 523 | 7.5 (4.1–10.9) | 0.75 (0.14–4.10) | 11.6 (6.6–14.4) | 474 | 6.8 (3.3–10.1) | 0.30 (0.02–1.69) | 15.5 (10.7–18.6) |
No | 1006 | 7.4 (3.2–11.0) | 0.72 (0.11–2.96) | 11.6 (6.9–16.2) | 959 | 6.8 (3.1–10.7) | 0.29 (0.03–2.54) | 15.5 (9.0–20.0) | |
p | 0.012 | 0.042 | 0.27 | 0.44 | 0.60 | 0.37 | |||
EPA and/or DHA | Yes | 43 | 7.3 (4.9–10.1) | 0.74 (0.25–1.95) | 11.6 (9.4–14.4) | 37 | 6.9 (5.4–8.7) | 0.30 (0.13–0.55) | 15.5 (12.6–18.3) |
No | 1485 | 7.4 (3.2–11.0) | 0.73 (0.11–4.10) | 11.6 (6.6–16.2) | 1395 | 6.8 (3.1–10.7) | 0.29 (0.02–2.54) | 15.4 (9.0–20.0) | |
p | 0.87 | 0.72 | 0.91 | 0.95 | 0.93 | 0.38 | |||
Breakfast skipper | |||||||||
Skipper | 235 | 7.3 (4.3–10.5) | 0.70 (0.25–2.96) | 11.7 (8.3–14.0) | 222 | 6.8 (3.4–9.2) | 0.29 (0.08–1.69) | 15.7 (9.7–20.0) | |
Eater | 1289 | 7.4 (3.2–11.0) | 0.73 (0.11–4.10) | 11.6 (6.6–16.2) | 1206 | 6.8 (3.1–10.7) | 0.29 (0.02–2.54) | 15.4 (9.0–19.6) | |
p | 0.028 | 0.18 | 0.40 | 0.97 | 0.65 | 0.010 | |||
Housewife | |||||||||
Yes | 771 | 7.4 (3.2–11.0) | 0.70 (0.11–4.10) | 11.7 (7.2–14.6) | 717 | 6.8 (3.3–10.7) | 0.28 (0.03–2.54) | 15.5 (9.0–20.0) | |
Yes | 752 | 7.4 (4.1–10.9) | 0.76 (0.16–3.44) | 11.6 (6.6–16.2) | 710 | 6.8 (3.1–10.5) | 0.30 (0.02–2.04) | 15.4 (9.7–19.6) | |
p | 0.17 | 0.0001 | 0.41 | 0.53 | 0.10 | 0.15 | |||
Sex of child | |||||||||
Male | 794 | 7.4 (3.2–10.8) | 0.74 (0.14–3.44) | 11.6 (6.6–14.6) | 735 | 6.9 (3.1–10.5) | 0.29 (0.05–2.54) | 15.2 (9.7–20.0) | |
Female | 749 | 7.4 (3.6–11.0) | 0.70 (0.11–4.10) | 11.6 (6.9–16.2) | 707 | 6.7 (3.3–10.7) | 0.29 (0.02–1.71) | 15.8 (9.0–19.9) | |
p | 0.045 | 0.0047 | 0.24 | 0.0002 | 0.49 | <.0001 | |||
Type of delivery | |||||||||
Transvaginal | 1318 | 7.4 (3.2–11.0) | 0.72 (0.11–3.44) | 11.6 (6.6–14.5) | 1243 | 6.8 (3.1–10.7) | 0.29 (0.02–2.54) | 15.4 (9.0–20.0) | |
Caesarean | 226 | 7.5 (4.6–10.7 | 0.76 (0.14–4.10) | 11.6 (7.9–16.2) | 199 | 6.6 (3.9–9.8) | 0.31 (0.07–1.36) | 15.7 (10.9–19.9) | |
p | 0.36 | 0.16 | 0.81 | 0.012 | 0.09 | 0.016 | |||
Season at blood collection | |||||||||
Spring | 357 | 7.3 (3.6–10.5) | 0.67 (0.16–2.16) | 11.6 (8.8–14.1) | - | - | - | - | |
Summer | 442 | 7.4 (4.4–10.9) | 0.69 (0.14–2.70) | 11.6 (7.1–14.2) | - | - | - | - | |
Autumn | 373 | 7.4 (3.2–10.8) | 0.77 (0.11–4.10) | 11.7 (6.6–14.3) | - | - | - | - | |
Winter | 355 | 7.5 (3.9–11.0) | 0.76 (0.23–2.68) | 11.5 (6.9–16.2) | - | - | - | - | |
p | 0.046 | 0.046 | 0.046 | - | - | - | - | ||
Season at delivery | |||||||||
Spring | - | - | - | - | 355 | 6.7 (4.0–9.8) | 0.28 (0.08–1.13) | 15.5 (10.5–20.0) | |
Summer | - | - | - | - | 328 | 6.8 (4.0–9.2) | 0.26 (0.02–2.04) | 15.4 (11.9–19.9) | |
Autumn | - | - | - | - | 404 | 7.0 (3.1–10.7) | 0.33 (0.04–2.54) | 15.6 (9.0–19.6) | |
Winter | - | - | - | - | 355 | 6.9 (3.3–10.5) | 0.30 (0.05–1.15) | 15.4 (10.7–18.6) | |
p | 0.10 | <.0001 | 0.98 |