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Table 4 Multivariate HR of Mortality According to Age at First Birth by Generation, the Ohsaki Cohort, Japan, 1995–2008

From: Age at first birth and long-term mortality for mothers: the Ohsaki cohort study

 

Age at first birth (years)

 

≤19

20–24

25–29

≥30

 
 

(n = 498)

(n = 13,607)

(n = 5,625)

(n = 894)

p-interaction

Born year (Age at baseline)

  < 1935 (≥60)

    

0.33

 No. of deaths

68

1169

528

104

 Multivariate HRa (95% CI)

1.18 (0.91–1.52)

1.00 (referent)

1.11 (1.00–1.24)

1.52 (1.22–1.89)

p-value

0.21

 

0.049

<0.01

1935–1955 (40–59)

 No. of deaths

8

183

89

16

 Multivariate HRa (95% CI)

1.01 (0.49–2.08)

1.00 (referent)

1.30 (1.00–1.69)

1.43 (0.83–2.46)

p-value

0.99

 

0.051

0.20

Birth year of the first child

  < 1960

    

0.58

 No. of deaths

73

1203

486

72

 Multivariate HRa (95% CI)

1.18 (0.92–1.51)

1.00 (referent)

1.05 (0.94–1.17)

1.33 (1.03–1.72)

p-value

0.19

 

0.38

0.03

1960-

 No. of deaths

3

149

131

48

 Multivariate HRa (95% CI)

0.61 (0.19–1.94)

1.00 (referent)

1.26 (0.98–1.63)

1.45 (0.97–2.16)

p-value

0.40

 

0.07

0.07

  1. Note. CI confidence interval, CVD cardiovascular disease, HR hazard ratio
  2. a The multivariate HR has been adjusted for age at baseline (continuous variable), number of births (1, 2, 3, or ≥4), use of oral contraceptives (yes or no), consumption of green vegetables, carrot or pumpkin, orange (for each food, ≤1–2 times per month, 1–2 times per week, 3–4 times per week, or almost every day), consumption of coffee (<1, 1–2, 3–4, or ≥5 cups per day), smoking status (never, former, or currently smoking), alcohol drinking (never, former, or currently drinking), body mass index at baseline in kg/m2 (<18.5, 18.5–24.9, or ≥25.0), increase in body weight since age 20 years (<10.0 or ≥10.0 kg), walking duration (<1 or ≥1 h per day), sleeping time in hours per day (continuous variable), defecation frequency (≥1 time per day, 1 time per 2–3 days, 1 time per 4–5 days or ≤1 time per 6 days), years of education (<10, 10–12, or ≥13 years), ikigai (yes, uncertain, or no), perceived mental stress (high, moderate, or low), and history of diabetes (yes or no)