Paraben exposure and semen quality of Japanese male partners of subfertile couples

Table 1 Urinary concentrations of each parabens of this subjects (n = 42) ^a

		Unit	GM	SD	Median	Min	Max	Detection rate (%)
MP	SG-adjusted	ng/mL	48.2	4.52	43.8	5.32	1042	100
MP	Creatine-adjusted	μg/g cre	37.4	4.47	28.6	3.11	571	100
EP	SG-adjusted	ng/mL	1.88	4.72	1.38	0.0895	157	100
EP	Creatine-adjusted	μg/g cre	1.46	4.91	1.11	0.0907	151	100
PP	SG-adjusted	ng/mL	1.13	6.75	1.49	<0.065	75.1	93
PP	Creatine-adjusted	μg/g cre	0.890	6.18	0.985	<0.065	70.3	93
BP	SG-adjusted	ng/mL	0.184	11.1	0.166	<0.0090	29.9	88
BP	Creatine-adjusted	μg/g cre	0.148	10.9	0.124	<0.0090	18.5	88
ETP ^b	SG-adjusted	μM	2.45	4.50	2.01	0.201	57.5	NA ^c
ETP ^b	Creatine-adjusted	μM	1.90	4.47	1.69	0.192	48.1	NA ^c

Abbreviations: MP methyl paraben, EP ethyl paraben, PP propyl paraben, BP butyl paraben, ETP estrogen-equivalent total paraben
^a Means and median were calculated by substituting 1/2 of LOD for subjects with urinary concentration below detection limit
^b ETP was the sum of the urinary concentrations of 4 parabens weighted by relative estrogenic activity obtained in a yeast estrogen screen assay by Routledge et al. [8]
^c Not Applicable

ISSN: 1347-4715