Influence of a 50bp Ins/Del polymorphism at promoter of the superoxide dismutase-1 on gene expression and risk of heroin dependency

Table 1 Association between the mRNA levels of SOD1 and the 50 bp Ins/Del genetic polymorphism at promoter region of the SOD1

Variables	Unstandardized coefficients		Standardized coefficients	t	P
Variables	B	SE	Beta
Constant	11.563	2.408	-	4.801	<0.001
SOD1 polymorphism^a	-3.340	0.640	-0.629	-5.217	<0.001
Age	-0.051	0.090	-0.069	-0.567	0.573
Gender^b	-0.658	0.601	-1.095	-1.095	0.279

Adjusted R² for model = 0.350; F = 9.261; df = 3, 43; P < 0.001
^a SOD1 polymorphism was included in analysis as number of the Del allele (0 and 1 used for Ins/Ins and Ins/Del genotypes, respectively)
^bGender was coded as 0 for females and 1 for males

ISSN: 1347-4715