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Table 2 Logistic regression analysis for association between gout and individual amino acids without and with adjustment for potential confounding demographic factors. The odds ratios were estimated per one SD change in the concentrations of corresponding amino acids

From: Alteration in plasma free amino acid levels and its association with gout

 

Model I a

Model II b

Model III c

Amino acid

OR

95% CI

P-value*

OR

95% CI

P-value*

OR

95% CI

P-value*

Lower

Upper

Lower

Upper

Lower

Upper

Ala

1.90

1.34

2.68

<.001

1.52

1.03

2.23

.035

1.31

0.88

1.95

.183

Gly

0.52

0.34

0.81

.003

0.60

0.38

0.94

.025

0.64

0.40

1.02

.061

Ile

2.16

1.57

2.97

<.001

1.78

1.25

2.53

.001

1.45

1.00 d

2.10

.049

Leu

2.14

1.53

2.99

<.001

1.69

1.17

2.44

.005

1.35

0.92

1.99

.127

Met

1.45

1.05

2.00

.026

1.13

0.79

1.62

.502

0.89

0.61

1.31

.571

Phe

1.86

1.37

2.54

<.001

1.60

1.14

2.26

.007

1.44

1.00 d

2.06

.050

Pro

1.59

1.16

2.17

.004

1.35

0.94

1.93

.108

1.06

0.70

1.60

.792

Ser

0.60

0.43

0.84

.003

0.67

0.48

0.95

.025

0.71

0.50

1.00

.048

Trp

1.99

1.37

2.88

<.001

1.53

1.03

2.26

.033

1.28

0.86

1.90

.221

Val

1.92

1.36

2.72

<.001

1.50

1.02

2.20

.037

1.20

0.80

1.80

.385

  1. *Bold P-values indicate statistically significant level of association with CI not including 1
  2. a Model I: without adjustment
  3. bModel II: adjusted for BMI, smoking status, and alcohol consumption
  4. cModel III: adjusted for gender, BMI, smoking status, and alcohol consumption
  5. dRounded to 1
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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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