Table 2 Characteristics of the study population according to RNF213 p.R4810K variant genotypes
GG | GA | P value | |
|---|---|---|---|
Number, n | 510 | 9 | |
Age (years), mean ± SD (range) | 63.0 ± 15.4 (21–91) | 62.0 ± 19.2 (34–88) | 0.9 |
Male sex, n (%) | 119 (23.3) | 1 (11.1) | |
BMI (kg/m2), mean ± SD | 22.0 ± 3.3 | 21.2 ± 3.2 | |
Hypertension, n (%) | 118 (23.1) | 1 (11.1) | |
Dyslipidemia, n (%) | 46 (9.0) | 0 (0) | |
Diabetes, n (%) | 29 (5.7) | 0 (0) | |
Kidney disease, n (%) | 22 (4.3) | 1 (11.1) | |
Liver disease, n (%) | 29 (5.7) | 0 (0) | |
Heart disease, n (%) | 58 (11.4) | 0 (0) | |
Drinking, n (%) | 269 (52.8) | 3 (33.3) | |
Smoking, n (%) | 96 (18.8) | 1 (11.1) | |
Other diseases, n a | Cancer, 15; tumor, 6; cerebral infarction, 6; anemia, 3; uterine fibroids, 2; stomach ulcer, 6; vestibular neuritis, 1; duodenal ulcers, 3; hemorrhoids, 1; tuberculosis, 3; connective tissue disease, 2; allergies, 64; joint disease, 5; hypothyroidism, 5; hyperuricemia, 1; reflux esophagitis, 1; osteoporosis, 5; cataract, 4; non-tuberculous bacteria disease, 1; macroglobulinemia, 1 | MMD, 1; osteoporosis, 1; connective tissue diseases 1 |