Table 1 Demographic characteristics and frequency of RNF213 p.R4810K in study participants

Number, n

519

Age (years), mean ± SD

62.99 ± 15.47

Male sex, n (%)

120 (23.12)

Hypertension, n (%)

119 (22.93)

Dyslipidemia, n (%)

46 (8.86)

Diabetes, n (%)

29 (5.59)

Drinking, n (%)

272 (52.40)

Smoking, n (%)

97 (18.69)

Kidney disease, n (%)

23 (4.43)

Liver disease, n (%)

29 (5.59)

Heart disease, n (%)

58 (11.18)

BMI (kg/m²), mean ± SD

21.96 ± 3.30

Genotype

 GG

510

 GA

9

 AA

0

 Carrier frequency of p.R4810K (%)

1.73

Allele

 G

1029

 A

9

Minor allele frequency (%)

0.87