Fig. 3
From: A new horizon of moyamoya disease and associated health risks explored through RNF213
Inhibition of angiogenesis by INFβ and lowered angiogenic activity of iPSECs established from controls and patients. iPSCs were established from controls and patients with MMD. Mature iPSECs were developed from iPSCs as reported by Hitomi et al. [24]. a Treatment with INFβ induced mRNA of RNF213 significantly. b Tube formation was lowered in patients. Treatment with INFβ inhibited tube formation for iPSEECs from patients. Cited from Kobayashi et al. [21]