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Table 1 Characteristics of original population

From: Metabolomic profiling reveals novel biomarkers of alcohol intake and alcohol-induced liver injury in community-dwelling men

Variable

Original population

Alcohol intake

Non-drinker (n = 231)

Low (n = 220)

Middle (n = 219)

High (n = 226)

Alcohol intake (g/day)a

N.A.

12.0 (1.0–24.6)

35.7 (25.0–46.0)

67.2 (46.1–205.1)

Age (years)b

62.5 (8.4)

63.0 (8.4)

62.6 (7.2)

62.0 (7.1)

Body mass index (kg/m2)b

23.8 (3.3)

23.4 (3.0)

23.5 (2.8)

23.4 (3.0)

Hypertension1, Yes

44.2 % (102/231)

47.7 % (105/220)

53.9 % (118/219)

59.3 % (134/226)

On medication, Yes

34.6 % (80/231)

31.4 % (69/220)

33.8 % (74/219)

38.9 % (88/226)

SBP (mmHg)c

123.9 (84–186)

129.9 (96-185)

132.4 (95–189)

133.8 (96–212)

DBP (mmHg)c

74.3 (51–106)

77.7 (47–113)

79.5 (54–112)

80.4 (56–109)

IGT2, Yes

24.2 % (56/231)

28.9 % (63/218)

26.0 % (57/219)

28.3 % (64/226)

On medication, Yes

10.4 % (24/231)

10.5 % (23/220)

9.6 % (21/219)

9.7 % (22/226)

FPG (mg/dL)c

100.8 (76–213)

103.8 (81–200)

102.6 (80–205)

103.9 (64–211)

HbA1c (%)c

5.8 (4.9–8.7)

5.8 (5.0–8.9)

5.7 (4.8–9.2)

5.7 (5.0–9.4)

Dyslipidemia3, Yes

55.8 % (129/231)

48.6 % (107/220)

40.2 % (88/219)

46.5 % (105/226)

On medication, Yes

19.9 % (46/231)

14.1 % (31/220)

12.8 % (28/219)

11.5 % (26/226)

Total cholesterol (mg/dL)b

201.1 (34.4)

204.5 (33.1)

205.4 (32.5)

205.4 (33.4)

LDL cholesterol (mg/dL)b

121.4 (30.2)

119.8 (29.1)

114.4 (29.4)

111.9 (30.5)

HDL cholesterol (mg/dL)b

57.4 (13.3)

62.3 (13.9)

68.1 (16.5)

69.0 (18.3)

Triglyceride (mg/dL)c

98.9 (25–447)

100.4 (41–872)

101.1 (30–564)

103.8 (37–1879)

AST (lU/L)c

22.3 (12–85)

23.6 (12–282)

24.7 (14–100)

27.2 (14–132)

ALT (lU/L)c

20.0 (7–92)

21.4 (7–145)

21.1 (5–91)

22.4 (8–98)

γ-GTP (lU/L)c

24.7 (10–477)

33.7 (10–913)

38.9 (12–428)

54.7 (13–1295)

Smoking, Yes

26.8 % (62/231)

20.0 % (44/220)

29.7 % (65/219)

36.7 % (83/226)

Ex

46.8 % (108/231)

52.3 % (115/220)

56.2 % (123/219)

52.7 % (119/226)

High daily activityd, Yes

20.0 % (45/225)

19.6 % (43/219)

28.9 % (63/218)

31.2 % (69/221)

High dietary intaked, Yes

29.0 % (67/231)

25.0 % (55/220)

26.0 % (57/219)

19.9 % (45/226)

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, γ-GTP gamma-glutamyl transpeptidase, DBP diastolic blood pressure, FPG fasting plasma glucose; HDL high-density lipoprotein, IGT impaired glucose tolerance, LDL low-density lipoprotein, SBP systolic blood pressure
  2. aReported as median (range)
  3. bReported as mean (standard deviation)
  4. cReported as geometric mean (range)
  5. dPercent and numbers of the highest quantile are shown
  6. 1Hypertension: Systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥90 mmHg or on medication
  7. 2Impaired glucose tolerance: Glucose ≥ 110 mg/dL, hemoglobinA1c ≥ 6.5 % or on medication
  8. 3Dyslipidemia: Triglyceride ≥ 150 mg/dL, LDL cholesterol ≥ 140 mg/dL, HDL cholesterol ≤ 40 mg/dL or on medication