Associations between aldehyde dehydrogenase 2 (ALDH2) genetic polymorphisms, drinking status, and hypertension risk in Japanese adult male workers: a case–control study

Table 3 Summary of multiple regression analysis for blood pressure by ALDH2 genetic polymorphism

Objective variables	Selected explanatory variables	β	SE	P value	Adjusted R ²
ALDH2 1/1 (n = 767)
SBP	Age	0.328	0.052	<0.001	0.172^*,a
SBP	BMI	0.256	0.151	<0.001
DBP	Age	0.363	0.038	<0.001	0.242^*,b
	BMI	0.314	0.111	<0.001
	Smoking status	−0.079	0.510	0.013
ALDH2 1/2 or 2/2 (n = 458)
SBP	Age	0.274	0.070	<0.001	0.177^*,c
	BMI	0.275	0.200	<0.001
	Amount of daily alcohol intake	0.084	0.026	0.047
DBP	Age	0.294	0.055	<0.001	0.236^*,d
	BMI	0.322	0.156	<0.001
	Smoking status	−0.118	0.668	0.004

* P < 0.001. Using the stepwise method. β standardized coefficient, SE standard error
^aMultiple regression model adjusted for smoking status, amount of daily alcohol intake
^bMultiple regression model adjusted for amount of daily alcohol intake
^cMultiple regression model adjusted for smoking status
^dMultiple regression model adjusted for amount of daily alcohol intake

ISSN: 1347-4715